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Zhang, Y.* ; Wu, S.* ; Pan, J.* ; Hoschar, S. ; Wang, Z.* ; Tu, R.* ; Ladwig, K.H.* ; Ma, W.*

The impact of the Type D Personality pattern on prehospital delay in patients suffering from acute myocardial infarction.

J. Thorac. Dis. 12, 4680-4689 (2020)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Background: The Type D Personality (TDP) has been specifically linked to acute myocardial infarction (AMI). However, the impact on prehospital delay of AMI patients is unclear. The aim of this study was to assess the relationship between TDP and pre-hospital delay time (PHT) in a Chinese population.Methods: A total of 256 AMI patients (47 women and 209 men) were taken from the Multicenter Delay in Patients Experiencing AMI in Shanghai (MEDEA FAR-EAST) study. Sociodemographic and psychobehavioral characteristics were assessed by bedside interviews and questionnaires. TDP was evaluated according to the Type D Personality Scale (DS14) subdivided in social inhibition (SI) and negative affectivity (NA). Based on a significant interaction analysis of TDP and sex on PHT, all analyses were stratified by sex.Results: PHT of female patients with TDP were substantially shorter compared to non-TDP female patients (108 vs. 281 min, P=0.029). In male patients, no effect of TDT on PHT was found. Spearman correlation analysis suggests that NA was negatively correlated with PHT (r=-0.358, P=0.014). Further age-adjusted logistic regression analyses showed that female patients with TDP were generally less likely to prehospital delay compared with non-TDP patients (OR =0.28; 95% CI, 0.08-0.98) and had a lower risk of PHT >360 minutes (OR =0.10; 95% CI, 0.01-0.91). However, statistical significance disappeared after adjustment for psychological factors (anxiety, depression, suboptimal wellbeing, cardiac denial and stress event).Conclusions: TDP is associated with less prehospital delay in female patients during AMI-an effect which may be particularly mediated by NA.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Type D Personality (tdp) ; Acute Myocardial Infarction (ami) ; Prehospital Delay ; Decision Time; Negative Affectivity; Social Inhibition; Depression; Mortality; Anxiety; Reperfusion; Time; Associations; Stress; Death
Sprache englisch
Veröffentlichungsjahr 2020
HGF-Berichtsjahr 2020
ISSN (print) / ISBN 2077-6624
e-ISSN 2072-1439
Quellenangaben Band: 12, Heft: 9, Seiten: 4680-4689 Artikelnummer: , Supplement: ,
Verlag Pioneer Bioscience Publ.
Verlagsort Hong Kong
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology (EPI)
POF Topic(s) 30202 - Environmental Health
Forschungsfeld(er) Genetics and Epidemiology
PSP-Element(e) G-504000-003
Förderungen German Heart Foundation
Science and Technology Committee Foundation of Shanghai, PR China
Scopus ID 85091662242
PubMed ID 33145041
Erfassungsdatum 2020-10-04