Zhang, Y.* ; Wu, S.* ; Pan, J.* ; Hoschar, S. ; Wang, Z.* ; Tu, R.* ; Ladwig, K.H.* ; Ma, W.*
     
 
    
        
The impact of the Type D Personality pattern on prehospital delay in patients suffering from acute myocardial infarction.
    
    
        
    
    
        
        J. Thorac. Dis. 12, 4680-4689 (2020)
    
    
    
		
		
			
				Background: The Type D Personality (TDP) has been specifically linked to acute myocardial infarction (AMI). However, the impact on prehospital delay of AMI patients is unclear. The aim of this study was to assess the relationship between TDP and pre-hospital delay time (PHT) in a Chinese population.Methods: A total of 256 AMI patients (47 women and 209 men) were taken from the Multicenter Delay in Patients Experiencing AMI in Shanghai (MEDEA FAR-EAST) study. Sociodemographic and psychobehavioral characteristics were assessed by bedside interviews and questionnaires. TDP was evaluated according to the Type D Personality Scale (DS14) subdivided in social inhibition (SI) and negative affectivity (NA). Based on a significant interaction analysis of TDP and sex on PHT, all analyses were stratified by sex.Results: PHT of female patients with TDP were substantially shorter compared to non-TDP female patients (108 vs. 281 min, P=0.029). In male patients, no effect of TDT on PHT was found. Spearman correlation analysis suggests that NA was negatively correlated with PHT (r=-0.358, P=0.014). Further age-adjusted logistic regression analyses showed that female patients with TDP were generally less likely to prehospital delay compared with non-TDP patients (OR =0.28; 95% CI, 0.08-0.98) and had a lower risk of PHT >360 minutes (OR =0.10; 95% CI, 0.01-0.91). However, statistical significance disappeared after adjustment for psychological factors (anxiety, depression, suboptimal wellbeing, cardiac denial and stress event).Conclusions: TDP is associated with less prehospital delay in female patients during AMI-an effect which may be particularly mediated by NA.
			
			
				
			
		 
		
			
				
					
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        Publikationstyp
        Artikel: Journalartikel
    
 
    
        Dokumenttyp
        Wissenschaftlicher Artikel
    
 
    
        Typ der Hochschulschrift
        
    
 
    
        Herausgeber
        
    
    
        Schlagwörter
        Type D Personality (tdp) ; Acute Myocardial Infarction (ami) ; Prehospital Delay ; Decision Time; Negative Affectivity; Social Inhibition; Depression; Mortality; Anxiety; Reperfusion; Time; Associations; Stress; Death
    
 
    
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        Sprache
        englisch
    
 
    
        Veröffentlichungsjahr
        2020
    
 
    
        Prepublished im Jahr 
        
    
 
    
        HGF-Berichtsjahr
        2020
    
 
    
    
        ISSN (print) / ISBN
        2077-6624
    
 
    
        e-ISSN
        2072-1439
    
 
    
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	    Band: 12,  
	    Heft: 9,  
	    Seiten: 4680-4689 
	    Artikelnummer: ,  
	    Supplement: ,  
	
    
 
  
        
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            Verlag
            Pioneer Bioscience Publ.
        
 
        
            Verlagsort
            Hong Kong
        
 
	
        
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        Begutachtungsstatus
        Peer reviewed
    
 
    
        Institut(e)
        Institute of Epidemiology (EPI)
    
 
    
        POF Topic(s)
        30202 - Environmental Health
    
 
    
        Forschungsfeld(er)
        Genetics and Epidemiology
    
 
    
        PSP-Element(e)
        G-504000-003
    
 
    
        Förderungen
        German Heart Foundation
Science and Technology Committee Foundation of Shanghai, PR China
    
 
    
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        Erfassungsdatum
        2020-10-04