Bespalov, A.* ; Bernard, R.* ; Gilis, A.* ; Gerlach, B.* ; Guillen, J.* ; Castagne, V.* ; Lefevre, I.* ; Ducrey, F.* ; Monk, L.* ; Bongiovanni, S.* ; Altevogt, B.* ; Arroyo Araujo, M.* ; Bikovski, L.* ; de Bruin, N.* ; Castanos-Velez, E.* ; Dityatev, A.* ; Emmerich, C.H.* ; Fares, R.* ; Ferland-Beckham, C.* ; Froger-Colléaux, C.* ; Gailus-Durner, V. ; Hölter, S.M. ; Hofmann, M.C.* ; Kabitzke, P.* ; Kas, M.J.H.* ; Kurreck, C.* ; Moser, P.* ; Pietraszek, M.* ; Popik, P.* ; Potschka, H.* ; Prado Montes de Oca, E.* ; Restivo, L.* ; Riedel, G.* ; Ritskes-Hoitinga, M.* ; Samardzic, J.* ; Schunn, M.* ; Stoeger, C. ; Voikar, V.* ; Vollert, J.* ; Wever, K.E.* ; Wuyts, K.* ; MacLeod, M.R.* ; Dirnagl, U.* ; Steckler, T.*
Introduction to the EQIPD quality system.
eLife 10:e63294 (2021)
While high risk of failure is an inherent part of developing innovative therapies, it can be reduced by adherence to evidence-based rigorous research practices. Numerous analyses conducted to date have clearly identified measures that need to be taken to improve research rigor. Supported through the European Union's Innovative Medicines Initiative, the EQIPD consortium has developed a novel preclinical research quality system that can be applied in both public and private sectors and is free for anyone to use. The EQIPD Quality System was designed to be suited to boost innovation by ensuring the generation of robust and reliable preclinical data while being lean, effective and not becoming a burden that could negatively impact the freedom to explore scientific questions. EQIPD defines research quality as the extent to which research data are fit for their intended use. Fitness, in this context, is defined by the stakeholders, who are the scientists directly involved in the research, but also their funders, sponsors, publishers, research tool manufacturers and collaboration partners such as peers in a multi-site research project. The essence of the EQIPD Quality System is the set of 18 core requirements that can be addressed flexibly, according to user-specific needs and following a user-defined trajectory. The EQIPD Quality System proposes guidance on expectations for quality-related measures, defines criteria for adequate processes (i.e., performance standards) and provides examples of how such measures can be developed and implemented. However, it does not prescribe any pre-determined solutions. EQIPD has also developed tools (for optional use) to support users in implementing the system and assessment services for those research units that successfully implement the quality system and seek formal accreditation. Building upon the feedback from users and continuous improvement, a sustainable EQIPD Quality System will ultimately serve the entire community of scientists conducting non-regulated preclinical research, by helping them generate reliable data that are fit for their intended use.
Impact Factor
Scopus SNIP
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Times Cited
Scopus
Cited By
Altmetric
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Typ der Hochschulschrift
Herausgeber
Schlagwörter
Neuroscience
Keywords plus
Sprache
englisch
Veröffentlichungsjahr
2021
Prepublished im Jahr
HGF-Berichtsjahr
2021
ISSN (print) / ISBN
2050-084X
e-ISSN
2050-084X
ISBN
Bandtitel
Konferenztitel
Konferzenzdatum
Konferenzort
Konferenzband
Quellenangaben
Band: 10,
Heft: ,
Seiten: ,
Artikelnummer: e63294
Supplement: ,
Reihe
Verlag
eLife Sciences Publications
Verlagsort
Sheraton House, Castle Park, Cambridge, Cb3 0ax, England
Tag d. mündl. Prüfung
0000-00-00
Betreuer
Gutachter
Prüfer
Topic
Hochschule
Hochschulort
Fakultät
Veröffentlichungsdatum
0000-00-00
Anmeldedatum
0000-00-00
Anmelder/Inhaber
weitere Inhaber
Anmeldeland
Priorität
Begutachtungsstatus
Peer reviewed
POF Topic(s)
30201 - Metabolic Health
30204 - Cell Programming and Repair
Forschungsfeld(er)
Genetics and Epidemiology
PSP-Element(e)
G-500600-001
G-500500-001
G-500692-001
Förderungen
Innovative Medicines Initiative
Copyright
Erfassungsdatum
2021-06-28