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Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement.
Nat. Biotechnol. 40, 422–431 (2022)
Aegilops tauschii, the diploid wild progenitor of the D subgenome of bread wheat, is a reservoir of genetic diversity for improving bread wheat performance and environmental resilience. Here we sequenced 242 Ae. tauschii accessions and compared them to the wheat D subgenome to characterize genomic diversity. We found that a rare lineage of Ae. tauschii geographically restricted to present-day Georgia contributed to the wheat D subgenome in the independent hybridizations that gave rise to modern bread wheat. Through k-mer-based association mapping, we identified discrete genomic regions with candidate genes for disease and pest resistance and demonstrated their functional transfer into wheat by transgenesis and wide crossing, including the generation of a library of hexaploids incorporating diverse Ae. tauschii genomes. Exploiting the genomic diversity of the Ae. tauschii ancestral diploid genome permits rapid trait discovery and functional genetic validation in a hexaploid background amenable to breeding.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Typ der Hochschulschrift
Herausgeber
Schlagwörter
Curl-mite; Resistance Gene; Hexaploid Wheat; Triticum-aestivum; Sequence; Polymorphisms; Progenitor; Diversity; Evolution; Trichomes
Keywords plus
Sprache
englisch
Veröffentlichungsjahr
2022
Prepublished im Jahr
2021
HGF-Berichtsjahr
2021
ISSN (print) / ISBN
1087-0156
e-ISSN
1546-1696
ISBN
Bandtitel
Konferenztitel
Konferzenzdatum
Konferenzort
Konferenzband
Quellenangaben
Band: 40,
Heft: 3,
Seiten: 422–431
Artikelnummer: ,
Supplement: ,
Reihe
Verlag
Nature Publishing Group
Verlagsort
New York, NY
Tag d. mündl. Prüfung
0000-00-00
Betreuer
Gutachter
Prüfer
Topic
Hochschule
Hochschulort
Fakultät
Veröffentlichungsdatum
0000-00-00
Anmeldedatum
0000-00-00
Anmelder/Inhaber
weitere Inhaber
Anmeldeland
Priorität
Begutachtungsstatus
Peer reviewed
POF Topic(s)
30202 - Environmental Health
Forschungsfeld(er)
Environmental Sciences
PSP-Element(e)
G-503500-002
Förderungen
National Science Foundation (NSF)
Royal Society
Department of Biotechnology, Ministry of Science and Technology (DBT)
Chinese Academy of Agricultural Sciences (CAAS)
RCUK | Biotechnology and Biological Sciences Research Council (BBSRC)
Copyright
Erfassungsdatum
2021-12-03