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Dean-Ben, X.L. ; Razansky, D. ; Ntziachristos, V.

The effects of acoustic attenuation in optoacoustic signals.

Phys. Med. Biol. 56, 6129-6148 (2011)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
In this paper, it is demonstrated that the effects of acoustic attenuation may play a significant role in establishing the quality of tomographic optoacoustic reconstructions. Accordingly, spatially dependent reduction of signal amplitude leads to quantification errors in the reconstructed distribution of the optical absorption coefficient while signal broadening causes loss of image resolution. Here we propose a correction algorithm for accounting for attenuation effects, which is applicable in both the time and frequency domains. It is further investigated which part of the optoacoustic signal spectrum is practically affected by those effects in realistic imaging scenarios. The validity and benefits of the suggested modelling and correction approaches are experimentally validated in phantom measurements.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter no keywords
Sprache englisch
Veröffentlichungsjahr 2011
HGF-Berichtsjahr 2011
ISSN (print) / ISBN 0031-9155
e-ISSN 1361-6560
Zeitschrift Physics in Medicine and Biology
Quellenangaben Band: 56, Heft: 18, Seiten: 6129-6148 Artikelnummer: , Supplement: ,
Verlag Institute of Physics Publishing (IOP)
Verlagsort Bristol
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Biological and Medical Imaging (IBMI)
POF Topic(s) 30205 - Bioengineering and Digital Health
Forschungsfeld(er) Enabling and Novel Technologies
PSP-Element(e) G-505500-001
PubMed ID 21873768
DOI 10.1088/0031-9155/56/18/021
Erfassungsdatum 2011-09-16
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