Achenbach, P. ; Berner, R.* ; Bonifacio, E.* ; Brämswig, S.* ; Braig, S.* ; Dunstheimer, D.* ; Ermer, U.* ; Ewald, D.* ; Gemulla, G.* ; Hauer, J.* ; Haupt, F. ; Haus, G.* ; Hubmann, M.* ; Hummel, S. ; Kandler, M.* ; Kordonouri, O.* ; Lange, K.* ; Laub, O.* ; Lorrmann, A.* ; Nellen-Hellmuth, N.* ; Sindichakis, M.* ; von dem Berge, T.* ; Warncke, K.* ; Weber, L.* ; Winkler, C. ; Wintermeyer, P.* ; Ziegler, A.-G.
Früherkennung von Typ-1-Diabetes durch
Inselautoantikörper-Screening – ein Positionspapier der
Fr1daPlex-Projektleiter und -Schulungszentren, des BVKJ Bayern und
PaedNetz Bayern e.V.
Gesundheitswesen, DOI: 10.1055/a-2320-2859 (2024)
This position paper is based on the authors' many years of clinical experience and basic science research on the diagnosis and treatment of children and adolescents with a presymptomatic early stage of type 1 diabetes. The benefits as well as potential disadvantages of early detection of type 1 diabetes by islet autoantibody screening are critically discussed. In addition, the perspectives of delaying the onset of the clinical metabolic disease through treatment with teplizumab are addressed. Today, we see the chance of a relevant improvement in the therapeutic options and life perspectives of affected children and adolescents. Important next steps for the implementation of islet autoantibody screening in Germany are the training of pediatricians who should inform families about the screening, the establishment of a few transregional laboratories that carry out the test, and the expansion of regional capacities for the training and care of children with an early stage of type 1 diabetes.
Impact Factor
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Times Cited
Scopus
Cited By
Altmetric
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Positionspapier
Typ der Hochschulschrift
Herausgeber
Schlagwörter
type 1 diabetes; early detection in children; presymptomatic early stage; islet autoantibody screening; type 1 diabetes; early detection in children; presymptomatic early stage; islet autoantibody screening; C-peptide Responses; Beta-cell Function; New-onset; Clinical Characteristics; Young-adults; Children; Ketoacidosis; Risk; Complications; Progression
Keywords plus
Sprache
deutsch
Veröffentlichungsjahr
2024
Prepublished im Jahr
0
HGF-Berichtsjahr
2024
ISSN (print) / ISBN
0941-3790
e-ISSN
1439-4421
ISBN
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Konferenztitel
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Band:
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Reihe
Verlag
Thieme
Verlagsort
Rudigerstr 14, D-70469 Stuttgart, Germany
Tag d. mündl. Prüfung
0000-00-00
Betreuer
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Prüfer
Topic
Hochschule
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Veröffentlichungsdatum
0000-00-00
Anmeldedatum
0000-00-00
Anmelder/Inhaber
weitere Inhaber
Anmeldeland
Priorität
Begutachtungsstatus
Peer reviewed
POF Topic(s)
30201 - Metabolic Health
90000 - German Center for Diabetes Research
Forschungsfeld(er)
Helmholtz Diabetes Center
PSP-Element(e)
G-502100-001
G-501900-211
Förderungen
Copyright
Erfassungsdatum
2024-06-11