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Lin, Y. ; Dai, R. ; Vogelaar, G. ; Rinkevich, Y.

Mini-review: Organ dependency on fascia connective tissue.

Am. J. Physiol.-Cell Physiol. 327, C357-C361 (2024)
Verlagsversion DOI PMC
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Fascia is a specialized connective tissue system that permiate, encapsulate, and interconnect between tissues and organs throughout the body. The fascia system regulates pain sensation, organ inflammation, trauma, and a fibrotic diseases. This mini-review summarizes recent findings from animal models, which reveal the inter-dependency between tissues/organs and the fascia system. special mechanisms of fascia response to skin inflammatory and fibrotic microenvironment via the dynamics within the fascia in trauma models, the functional heterogeneity of its fascia-born fibroblasts, and cellular communication, to highlight the significance of their stage-specific differentiation to disease progression. Understanding the molecular mechanisms and cellular processes within the fascia microenvironment, may serve as basis for future clinical translation.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Fascia ; Fascia Fibroblast ; Organ Dependence ; Wound Healing
Sprache englisch
Veröffentlichungsjahr 2024
HGF-Berichtsjahr 2024
ISSN (print) / ISBN 0363-6143
e-ISSN 1522-1563
Zeitschrift American Journal of Physiology - Cell Physiology
Quellenangaben Band: 327, Heft: 2, Seiten: C357-C361 Artikelnummer: , Supplement: ,
Verlag American Physiological Society
Verlagsort 6120 Executive Blvd, Suite 600, Rockville, Md, United States
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Regenerative Biology and Medicine (IRBM)
POF Topic(s) 30202 - Environmental Health
Forschungsfeld(er) Lung Research
PSP-Element(e) G-509400-001
Förderungen European Foundation for the Study of Diabetes (EFSD)
DOI 10.1152/ajpcell.00350.2024
WOS ID 001290450000002
Scopus ID 85200426680
PubMed ID 38912738
Erfassungsdatum 2024-07-16
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