Teboul, L.* ; Amos-Landgraf, J.* ; Benavides, F.J.* ; Birling, M.C.* ; Brown, S.D.M.* ; Bryda, E.* ; Bunton-Stasyshyn, R.* ; Chin, H.-J.* ; Crispo, M.* ; Delerue, F.* ; Dobbie, M.* ; Franklin, C.L.* ; Fuchtbauer, E.-M.* ; Gao, X.* ; Golzio, C.* ; Haffner, R.* ; Hérault, Y.* ; Hrabě de Angelis, M. ; Lloyd, K.C.K.* ; Magnuson, T.R.* ; Montoliu, L.* ; Murray, S.A.* ; Nam, K.H.* ; Nutter, L.M.J.* ; Pailhoux, E.* ; Pardo Manuel de Villena, F.* ; Peterson, K.* ; Reinholdt, L.* ; Sedlacek, R.* ; Seong, J.K.* ; Shiroishi, T.* ; Smith, C.* ; Takeo, T.* ; Tinsley, L.* ; Vilotte, J.L.* ; Warming, S.* ; Wells, S.* ; Whitelaw, C.B.* ; Yoshiki, A.* ; Pavlovic, G.*
Improving laboratory animal genetic reporting: LAG-R guidelines.
Nat. Commun. 15:5574 (2024)
The biomedical research community addresses reproducibility challenges in animal studies through standardized nomenclature, improved experimental design, transparent reporting, data sharing, and centralized repositories. The ARRIVE guidelines outline documentation standards for laboratory animals in experiments, but genetic information is often incomplete. To remedy this, we propose the Laboratory Animal Genetic Reporting (LAG-R) framework. LAG-R aims to document animals' genetic makeup in scientific publications, providing essential details for replication and appropriate model use. While verifying complete genetic compositions may be impractical, better reporting and validation efforts enhance reliability of research. LAG-R standardization will bolster reproducibility, peer review, and overall scientific rigor.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Typ der Hochschulschrift
Herausgeber
Schlagwörter
Mutation; Reproducibility; Husbandry; Phenotype; Scale; Mice
Keywords plus
Sprache
englisch
Veröffentlichungsjahr
2024
Prepublished im Jahr
0
HGF-Berichtsjahr
2024
ISSN (print) / ISBN
2041-1723
e-ISSN
2041-1723
ISBN
Bandtitel
Konferenztitel
Konferzenzdatum
Konferenzort
Konferenzband
Quellenangaben
Band: 15,
Heft: 1,
Seiten: ,
Artikelnummer: 5574
Supplement: ,
Reihe
Verlag
Nature Publishing Group
Verlagsort
London
Tag d. mündl. Prüfung
0000-00-00
Betreuer
Gutachter
Prüfer
Topic
Hochschule
Hochschulort
Fakultät
Veröffentlichungsdatum
0000-00-00
Anmeldedatum
0000-00-00
Anmelder/Inhaber
weitere Inhaber
Anmeldeland
Priorität
Begutachtungsstatus
Peer reviewed
POF Topic(s)
30201 - Metabolic Health
Forschungsfeld(er)
Genetics and Epidemiology
PSP-Element(e)
G-500600-001
Förderungen
Ministry of Education, Youth and Sports of the Czech Republic
Czech Academy of Sciences
National Science and Technology Council, Taiwan
Neogen Inc., Lincoln, NE
NIH
Copyright
Erfassungsdatum
2024-07-08