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Suri, C.* ; Pande, B.* ; Sahithi, L.S.* ; Sahu, T.* ; Verma, H.K.

Interplay between lung diseases and viral infections: A comprehensive review.

Microorganisms 12:2030 (2024)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
The intricate relationship between chronic lung diseases and viral infections is a significant concern in respiratory medicine. We explore how pre-existing lung conditions, including chronic obstructive pulmonary disease, asthma, and interstitial lung diseases, influence susceptibility, severity, and outcomes of viral infections. We also examine how viral infections exacerbate and accelerate the progression of lung disease by disrupting immune responses and triggering inflammatory pathways. By summarizing current evidence, this review highlights the bidirectional nature of these interactions, where underlying lung diseasesincrease vulnerability to viral infections, while these infections, in turn, worsen the clinical course. This review underscores the importance of preventive measures, such as vaccination, early detection, and targeted therapies, to mitigate adverse outcomes in patients with chronic lung conditions. The insights provided aim to inform clinical strategies that can improve patient management and reduce the burden of chronic lung diseases exacerbated by viral infections.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Exacerbation ; Interaction ; Lung Disease ; Pathway ; Therapeutics ; Viral Infection
Sprache englisch
Veröffentlichungsjahr 2024
HGF-Berichtsjahr 2024
ISSN (print) / ISBN 2076-2607
e-ISSN 2076-2607
Zeitschrift Microorganisms
Quellenangaben Band: 12, Heft: 10, Seiten: , Artikelnummer: 2030 Supplement: ,
Verlag MDPI
Verlagsort Basel
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Lung Health and Immunity (LHI)
POF Topic(s) 80000 - German Center for Lung Research
Forschungsfeld(er) Lung Research
PSP-Element(e) G-501810-007
DOI 10.3390/microorganisms12102030
Scopus ID 85207686569
PubMed ID 39458339
Erfassungsdatum 2024-10-28
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