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Horvath, P. ; Coscia, F.*

Spatial proteomics in translational and clinical research.

Mol. Syst. Biol. 21, 526 - 530 (2025)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Spatial proteomics offers unprecedented insights into the localization, quantity, and interactions of proteins within cells and tissues, thereby enabling researchers and clinicians to map protein networks with high precision. This powerful approach is currently revolutionizing our understanding of cellular organization and function (Method of the Year 2024: spatial proteomics, 2024), and providing deeper insights into how protein distribution and dynamics contribute to physiological and pathological processes. Here, we discuss recent advances in targeted and untargeted (exploratory) spatial proteomics, shed light on emerging multiscale approaches for tissue profiling, and highlight their translational potential.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Editorial
Sprache englisch
Veröffentlichungsjahr 2025
HGF-Berichtsjahr 2025
ISSN (print) / ISBN 1744-4292
e-ISSN 1744-4292
Zeitschrift Molecular Systems Biology
Quellenangaben Band: 21, Heft: , Seiten: 526 - 530 Artikelnummer: , Supplement: ,
Verlag EMBO Press
Verlagsort Campus, 4 Crinan St, London, N1 9xw, England
Begutachtungsstatus Peer reviewed
Institut(e) Institute of AI for Health (AIH)
POF Topic(s) 30205 - Bioengineering and Digital Health
Forschungsfeld(er) Enabling and Novel Technologies
PSP-Element(e) G-540009-001
Förderungen European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program
Horizon-BIALYMPH (NRDIO)
Horizon-SYMMETRY (NRDIO)
Horizon-SWEEPICS
H2020-Fair-CHARM
HAS-NAP3
NKKP-ADVANCED
Finnish Cancer Society (Cancer Foundation Finland)
Federal Ministry of Education and Research (BMBF), as part of the National Research Initiatives for Mass Spectrometry in Systems Medicine
National Research, Development and Innovation Office
DOI 10.1038/s44320-025-00101-9
WOS ID 001466390700001
Scopus ID 105002592565
PubMed ID 40229558
Erfassungsdatum 2025-05-10
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