Histone modifications in development.
Development 152:dev204384 (2025)
In eukaryotic cells, the genetic material is organized into chromatin, which consists mainly of DNA, histones and chromatin-associated proteins. An important regulator of chromatin structure and function are histone post-translational modifications, which can shape gene expression patterns and control the epigenetic landscape. Here, we summarize the role of some key histone modifications in animal development, with a focus on the two best-studied types of histone modifications: lysine methylation and acylations, specifically, acetylation.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Typ der Hochschulschrift
Herausgeber
Schlagwörter
Acetylation ; Histone Modification ; Methylation ; Mutation; Molecular-mechanisms; Chromatin-structure; Gene-expression; Lateral Surface; Acetylation; H3; Phosphorylation; Transcription; Nucleosome; Differentiation
Keywords plus
Sprache
englisch
Veröffentlichungsjahr
2025
Prepublished im Jahr
0
HGF-Berichtsjahr
2025
ISSN (print) / ISBN
0950-1991
e-ISSN
1477-9129
ISBN
Bandtitel
Konferenztitel
Konferzenzdatum
Konferenzort
Konferenzband
Quellenangaben
Band: 152,
Heft: 12,
Seiten: ,
Artikelnummer: dev204384
Supplement: ,
Reihe
Verlag
Company of Biologists
Verlagsort
Bidder Building, Station Rd, Histon, Cambridge Cb24 9lf, England
Tag d. mündl. Prüfung
0000-00-00
Betreuer
Gutachter
Prüfer
Topic
Hochschule
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Veröffentlichungsdatum
0000-00-00
Anmeldedatum
0000-00-00
Anmelder/Inhaber
weitere Inhaber
Anmeldeland
Priorität
Begutachtungsstatus
Peer reviewed
POF Topic(s)
30203 - Molecular Targets and Therapies
Forschungsfeld(er)
Helmholtz Diabetes Center
PSP-Element(e)
G-502800-001
Förderungen
Helmholtz-Gemeinschaft
Copyright
Erfassungsdatum
2025-07-08