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Wichmann, H.-E. ; Kaaks, R.* ; Hoffmann, W.* ; Jöckel, K.-H.* ; Greiser, K.H.* ; Linseisen, J.

Die nationale Kohorte.

Bundesgesundheitsbl.-Gesund. 55, 781-787 (2012)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
The German National Cohort (GNC) is a joint interdisciplinary endeavour of scientists from the Helmholtz Association, universities and other German research institutes. Its aim is to investigate the development of major chronic diseases (cardiovascular diseases, cancer, diabetes, neurodegenerative psychiatric diseases, pulmonary and infectious diseases), the subclinical stages and functional changes. In 18 study centres across Germany, a representative sample of the general population will be drawn to recruit in total 200,000 men and women aged 20-69 years. In addition to interviews and questionnaires, the baseline assessment includes a series of medical examinations and the collection of a diverse range of biomaterials. In 20% of the participants, an intensified assessment programme is foreseen. Also in 40,000 participants, magnetic resonance imaging of the whole body, heart and brain will be performed. After 5 years, a follow-up examination will be performed in all subjects and active follow-up by postal questionnaires is planned every 2-3 years. The GNC will provide an excellent basis for future population-based epidemiology in Germany and results will help identify new and tailored strategies for prevention, prediction and early detection of major diseases.
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0.658
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61
68
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Population-based Cohort ; Chronic Disease ; Life-style Factors ; Magnet Resonance Imaging ; Subclinical Stages ; Functional Changes
Sprache
Veröffentlichungsjahr 2012
HGF-Berichtsjahr 2012
ISSN (print) / ISBN 1436-9990
e-ISSN 1437-1588
Quellenangaben Band: 55, Heft: 6-7, Seiten: 781-787 Artikelnummer: , Supplement: ,
Verlag Springer
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology (EPI)
Cooperation Group Comprehensive Molecular Analytics (CMA)
POF Topic(s)
30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
30202 - Environmental Health
Forschungsfeld(er)
Genetics and Epidemiology
Environmental Sciences
PSP-Element(e) G-503900-002
G-503990-001
G-504500-001
Scopus ID 84865742184
Erfassungsdatum 2012-07-19