PuSH - Publikationsserver des Helmholtz Zentrums München

Genomweite Assoziationsstudien (GWAS) - Möglichkeiten und Grenzen.

BioSpektrum 18, 508-510 (2012)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
GWAS have brought many successes to detect DNA-variants for common diseases and other traits. Feasibility to genotype a large amount of SNPs cost efficiently in big populations with various study designs benefits GWAS in contrast to candidate gene studies. However, they only explain a small proportion of estimated heritability so far. It’s still a long way to go, to develop methods to discover false negative signals, find other impact e. g. from epigenetics or gene-environment interaction as well as to translate all findings into better understanding of disease and clinical practice.
Altmetric
Weitere Metriken?
Zusatzinfos bearbeiten [➜Einloggen]
Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
ISSN (print) / ISBN 0947-0867
e-ISSN 1868-6249
Zeitschrift BioSpektrum
Quellenangaben Band: 18, Heft: 5, Seiten: 508-510 Artikelnummer: , Supplement: ,
Verlag Springer
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed