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    Review of novel aspects of the regulation of ghrelin secretion.
        
        Curr. Drug Metab. 15, 398-413 (2014)
    
    
    
				The role of ghrelin in regulating metabolism and energy balance has been a subject of intense focus ever since its discovery. Ghrelin regulates energy balance in the short term by induction of appetite and in the longer term by increasing body weight and adiposity. It is the only known peripheral orexigenic hormone and one of the most potent endogenous orexigenic factors discovered to date. However, whilst extensively studied, the mechanism of ghrelin secretion is not well understood. A better understanding of the pathways controlling ghrelin secretion could be useful in the development of new therapeutic approaches to appetite-related disorders. Here, we discuss current knowledge of the processes that control ghrelin secretion, focusing on neural, chemical and hormonal stimuli. In addition, we share our view on the potential of targeting ghrelin for the treatment of eating disorders such as obesity, anorexia nervosa and cachexia.
			
			
		Impact Factor
					Scopus SNIP
					Web of Science
Times Cited
					Times Cited
Scopus
Cited By
					
					Cited By
Altmetric
					
				3.487
					1.297
					23
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        Publikationstyp
        Artikel: Journalartikel
    
 
    
        Dokumenttyp
        Review
    
 
     
    
     
     
    
    
        Sprache
        englisch
    
 
    
        Veröffentlichungsjahr
        2014
    
 
     
    
        HGF-Berichtsjahr
        2014
    
 
    
    
        ISSN (print) / ISBN
        1389-2002
    
 
    
        e-ISSN
        1875-5453
    
 
     
     
     
	     
	 
	 
    
        Zeitschrift
        Current Drug Metabolism
    
 
		
    
        Quellenangaben
        
	    Band: 15,  
	    Heft: 4,  
	    Seiten: 398-413 
	    
	    
	
    
 
  
         
        
            Verlag
            Bentham Science Publishers
        
 
        
            Verlagsort
            Hilversum [u.a.]
        
 
	
         
         
         
         
         
	
         
         
         
    
         
         
         
         
         
         
         
    
        Begutachtungsstatus
        Peer reviewed
    
 
    
        Institut(e)
        Institute of Diabetes and Obesity (IDO)
    
 
    
        POF Topic(s)
        90000 - German Center for Diabetes Research
30201 - Metabolic Health
 
    30201 - Metabolic Health
        Forschungsfeld(er)
        Helmholtz Diabetes Center
    
 
    
        PSP-Element(e)
        G-501900-221
G-502200-001
 
     
     	
    G-502200-001
        PubMed ID
        24813425
    
    
    
        WOS ID
        WOS:000344817400005
    
    
        Erfassungsdatum
        2014-08-26