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Natural history of type 1 diabetes.
Diabetes 54, S25-S31 (2005)
The natural history of autoimmune type 1 diabetes in children is associated with the appearance of islet autoantibodies early in life, which is influenced by genetic and environmental factors. Once islet autoantibodies have developed, the progression to diabetes in antibody-positive individuals is determined by the age of antibody appearance and by the magnitude of the autoimmunity, in turn related to the age of the subject. Characteristics that describe the magnitude of the autoimmunity can stage progression to type 1 diabetes in islet autoantibody–positive subjects regardless of genetic background or age.
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Anmerkungen
Besondere Publikation
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Sprache
englisch
Veröffentlichungsjahr
2005
HGF-Berichtsjahr
0
ISSN (print) / ISBN
0012-1797
e-ISSN
1939-327X
Zeitschrift
Diabetes
Quellenangaben
Band: 54,
Heft: S2,
Seiten: S25-S31
Verlag
American Diabetes Association
Verlagsort
Alexandria, VA.
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Diabetes Research (IDF)
Institute of Diabetes and Obesity (IDO)
Institute of Pancreatic Islet Research (IPI)
Institute of Diabetes and Obesity (IDO)
Institute of Pancreatic Islet Research (IPI)
POF Topic(s)
30201 - Metabolic Health
30502 - Diabetes: Pathophysiology, Prevention and Therapy
30502 - Diabetes: Pathophysiology, Prevention and Therapy
Forschungsfeld(er)
Helmholtz Diabetes Center
PSP-Element(e)
G-502100-001
G-502290-001
G-502290-001
Erfassungsdatum
2005-12-31