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Science 345:1251788 (2014)
An ordered draft sequence of the 17-gigabase hexaploid bread wheat (Triticum aestivum) genome has been produced by sequencing isolated chromosome arms. We have annotated 124,201 gene loci distributed nearly evenly across the homeologous chromosomes and subgenomes. Comparative gene analysis of wheat subgenomes and extant diploid and tetraploid wheat relatives showed that high sequence similarity and structural conservation are retained, with limited gene loss, after polyploidization. However, across the genomes there was evidence of dynamic gene gain, loss, and duplication since the divergence of the wheat lineages. A high degree of transcriptional autonomy and no global dominance was found for the subgenomes. These insights into the genome biology of a polyploid crop provide a springboard for faster gene isolation, rapid genetic marker development, and precise breeding to meet the needs of increasing food demand worldwide.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Times Cited
Scopus
Cited By
Cited By
Altmetric
31.477
7.966
277
1184
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Sprache
englisch
Veröffentlichungsjahr
2014
HGF-Berichtsjahr
2014
ISSN (print) / ISBN
0036-8075
e-ISSN
1095-9203
Zeitschrift
Science
Quellenangaben
Band: 345,
Heft: 6194,
Artikelnummer: 1251788
Verlag
American Association for the Advancement of Science (AAAS)
Begutachtungsstatus
Peer reviewed
Institut(e)
Research Unit Plant Genome and Systems Biology (PGSB)
Institute of Epidemiology (EPI)
Institute of Environmental Medicine (IEM)
Institute of Epidemiology (EPI)
Institute of Environmental Medicine (IEM)
POF Topic(s)
30202 - Environmental Health
Forschungsfeld(er)
Environmental Sciences
Genetics and Epidemiology
Allergy
Genetics and Epidemiology
Allergy
PSP-Element(e)
G-503500-002
G-504091-002
G-503400-001
G-504091-002
G-503400-001
WOS ID
WOS:000343420300004
WOS ID
WOS:000339400700040
Scopus ID
84904382612
PubMed ID
25035500
Erfassungsdatum
2014-09-24