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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Headspace measurements of irradiated in vitro cultured cells using PTR-MS.
Radiat. Environ. Biophys. 50, 209-217 (2011)
A pilot study was performed to evaluate a new concept for a radiation biodosimetry method. Proton transfer reaction-mass spectrometry (PTR-MS) was used to find out whether radiation induces changes in the composition of volatile organic compounds (VOCs) in the headspace of in vitro cultured cells. Two different cell lines, retinal pigment epithelium cells hTERT-RPE1 and lung epithelium cells A-549, were irradiated with gamma radiation at doses of 4 Gy and 8 Gy. For measuring the cell-specific effects, the VOC concentrations in the headspace of flasks containing cells plus medium, as well as of flasks containing pure medium were analyzed for changes before and after irradiation. No significant radiation-induced alterations in VOC concentrations in the headspace could be observed after irradiation.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Times Cited
Scopus
Cited By
Cited By
Altmetric
1.635
0.982
6
10
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
volatile organic compounds (VOCs); PTR-MS; cell culture; radiation biodosimetry
Sprache
Veröffentlichungsjahr
2011
Prepublished im Jahr
2010
HGF-Berichtsjahr
2010
ISSN (print) / ISBN
0301-634X
e-ISSN
1432-2099
Zeitschrift
Radiation and Environmental Biophysics
Quellenangaben
Band: 50,
Heft: 1,
Seiten: 209-217
Verlag
Springer
Begutachtungsstatus
Peer reviewed
Institut(e)
Research Unit Medical Radiation Physics and Diagnostics (AMSD)
Institute of Radiation Biology (ISB)
Institute of Radiation Biology (ISB)
POF Topic(s)
30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
30202 - Environmental Health
30202 - Environmental Health
Forschungsfeld(er)
Radiation Sciences
PSP-Element(e)
G-503600-001
G-503600-002
G-500200-001
G-500200-002
G-503600-002
G-500200-001
G-500200-002
PubMed ID
20821023
Scopus ID
79952439754
Erfassungsdatum
2010-12-10