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Molecular tools in the detection of micrometastatic cancer cells - technical aspects and clinical relevance.
Recent Results Cancer Res. 158, 181-186 (2001)
The frequent failure to reduce the mortality due to epithelial cancers by common medical intervention results primarily from early dissemination of cancer cells, which is missed by conventional diagnostic procedures used for tumor staging. Individual carcinoma cells present in regional lymph nodes, blood or distant organs (e.g., bone marrow) can be detected by sensitive immunologic or molecular methods. Here, we review recently developed molecular assays for the detection of individual micrometastatic cancer cells and their clinical application in patients with epithelial tumors.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Sprache
englisch
Veröffentlichungsjahr
2001
HGF-Berichtsjahr
0
ISSN (print) / ISBN
0080-0015
Zeitschrift
Recent Results in Cancer Research
Quellenangaben
Band: 158,
Seiten: 181-186
Verlag
Springer
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Pancreatic Islet Research (IPI)
PubMed ID
11092045
Erfassungsdatum
2001-12-31