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Viganò, F.* ; Dimou, L.

The heterogeneous nature of NG2-glia.

Brain Res. 1638, 129-137 (2016)
Postprint DOI PMC
Open Access Green
In the central nervous system, NG2-glia are the cells responsible for the generation of mature oligodendrocytes during development and adulthood. Some studies could show that NG2-glia can give origin also to astrocytes and neurons, a property that makes them similar to neural stem cells. Beside their important role as progenitors, NG2-glia are believed also to have more functions due to their unique interaction with neurons through synapses. It is however not clear whether these features are common to all NG2-glia or different subpopulations of NG2-glia devoted to different functions exist. Therefore the aim of this review is to highlight the state of the art on NG2-glia heterogeneity from development to adulthood and in different brain areas, and discuss the impact of it on our understanding of the glial neurobiology. This article is part of a Special Issue entitled SI:NG2-glia(Invited only).
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Developmental Stages ; Differentiation ; Heterogeneity ; Proliferation ; Regional Differences; Oligodendrocyte Progenitor Cells; Adult Cerebral-cortex; Ng2 Cells; Subventricular Zone; Stem-cells; White-matter; Gray-matter; In-vivo; Piriform Cortex; Precursor Cells
ISSN (print) / ISBN 0006-8993
e-ISSN 1872-6240
Zeitschrift Brain Research
Quellenangaben Band: 1638, Heft: , Seiten: 129-137 Artikelnummer: , Supplement: ,
Verlag Elsevier
Verlagsort Amsterdam
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Stem Cell Research (ISF)