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Iron in restless legs syndrome.

Mov. Disord. Clin. Pract. 1, 161-172 (2014)
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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
A link between restless legs syndrome (RLS) and iron has been recognized for several decades. Yet, the precise role that iron or other components of iron metabolism play in bringing about RLS is still a matter of debate. During the last few years, many new pieces of evidence from genetics, pathology, imaging, and clinical studies have surfaced. However, the way this evidence fits into the larger picture of RLS as a disease is not always easily understood. To provide a better understanding of the complex interplay between iron metabolism and RLS and highlight areas that need further elucidation, we systematically and critically review the current literature on the role of iron in RLS pathophysiology and treatment with a special emphasis on genetics, neuropathology, cell and animal models, imaging studies, and therapy.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Genetics ; Imaging ; Iron ; Restless Legs Syndrome ; Therapy
Sprache englisch
Veröffentlichungsjahr 2014
HGF-Berichtsjahr 2014
ISSN (print) / ISBN 2330-1619
e-ISSN 2330-1619
Quellenangaben Band: 1, Heft: 3, Seiten: 161-172 Artikelnummer: , Supplement: ,
Verlag Wiley
Verlagsort New York, NY
Begutachtungsstatus Peer reviewed
POF Topic(s) 30205 - Bioengineering and Digital Health
30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
Forschungsfeld(er) Genetics and Epidemiology
PSP-Element(e) G-503200-001
G-500700-001
Scopus ID 85067375765
Erfassungsdatum 2019-07-01