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Sheng, M.* ; Ertürk, A.

Long-term depression: A cell biological view.

Philos. Trans. R. Soc. B - Biol. Sci. 369:20130138 (2014)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Recent studies of the molecular mechanisms of long-term depression (LTD) suggest a crucial role for the signalling pathways of apoptosis (programmed cell death) in the weakening and elimination of synapses and dendritic spines. With this backdrop, we suggest that LTD can be considered as the electrophysiological aspect of a larger cell biological programme of synapse involution, which uses localized apoptotic mechanisms to sculpt synapses and circuits without causing cell death.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Korrespondenzautor
Schlagwörter Caspase ; Dendritic Spine ; Local Apoptosis ; Long-term Depression ; Long-term Potentiation ; Spine Elimination
ISSN (print) / ISBN 0962-8436
e-ISSN 1471-2970
Quellenangaben Band: 369, Heft: 1633, Seiten: , Artikelnummer: 20130138 Supplement: ,
Verlag Royal Society of London
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute for Tissue Engineering and Regenerative Medicine (ITERM)