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Williams, R.H. ; Riedemann, T.*

Development, diversity and death of mge-derived cortical interneurons.

Int. J. Mol. Sci. 22:9297 (2021)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
In the mammalian brain, cortical interneurons (INs) are a highly diverse group of cells. A key neurophysiological question concerns how each class of INs contributes to cortical circuit function and whether specific roles can be attributed to a selective cell type. To address this question, researchers are integrating knowledge derived from transcriptomic, histological, electrophysiological, developmental, and functional experiments to extensively characterise the different classes of INs. Our hope is that such knowledge permits the selective targeting of cell types for therapeutic endeavours. This review will focus on two of the main types of INs, namely the parvalbumin (PV+) or somatostatin (SOM+)-containing cells, and summarise the research to date on these classes.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Cortical Interneurons ; Gaba ; Interneuron Development ; Interneuron Diversity ; Parvalbumin ; Somatostatin; Expressing Gabaergic Interneurons; Medial Ganglionic Eminence; Transcriptomic Cell-types; Long-range Projections; Short-term Plasticity; Cat Visual-cortex; Basket Cells; Neurogliaform Cells; Inhibitory Neurons; Layer-v
Sprache englisch
Veröffentlichungsjahr 2021
HGF-Berichtsjahr 2021
ISSN (print) / ISBN 1661-6596
e-ISSN 1422-0067
Quellenangaben Band: 22, Heft: 17, Seiten: , Artikelnummer: 9297 Supplement: ,
Verlag MDPI
Verlagsort Basel
Begutachtungsstatus Peer reviewed
POF Topic(s) 30205 - Bioengineering and Digital Health
Forschungsfeld(er) Genetics and Epidemiology
PSP-Element(e) G-555100-001
Förderungen Helmholtz Zentrum Muenchen
ERC
Friedrich-Baur Stiftung
Scopus ID 85113473815
PubMed ID 34502208
Erfassungsdatum 2021-09-09