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Williams, R.H. ; Riedemann, T.*

Development, diversity and death of mge-derived cortical interneurons.

Int. J. Mol. Sci. 22:9297 (2021)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
In the mammalian brain, cortical interneurons (INs) are a highly diverse group of cells. A key neurophysiological question concerns how each class of INs contributes to cortical circuit function and whether specific roles can be attributed to a selective cell type. To address this question, researchers are integrating knowledge derived from transcriptomic, histological, electrophysiological, developmental, and functional experiments to extensively characterise the different classes of INs. Our hope is that such knowledge permits the selective targeting of cell types for therapeutic endeavours. This review will focus on two of the main types of INs, namely the parvalbumin (PV+) or somatostatin (SOM+)-containing cells, and summarise the research to date on these classes.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Korrespondenzautor
Schlagwörter Cortical Interneurons ; Gaba ; Interneuron Development ; Interneuron Diversity ; Parvalbumin ; Somatostatin; Expressing Gabaergic Interneurons; Medial Ganglionic Eminence; Transcriptomic Cell-types; Long-range Projections; Short-term Plasticity; Cat Visual-cortex; Basket Cells; Neurogliaform Cells; Inhibitory Neurons; Layer-v
ISSN (print) / ISBN 1422-0067
e-ISSN 1661-6596
Zeitschrift International Journal of Molecular Sciences
Quellenangaben Band: 22, Heft: 17, Seiten: , Artikelnummer: 9297 Supplement: ,
Verlag MDPI
Verlagsort Basel
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Neurogenomics (ING)
Förderungen Helmholtz Zentrum Muenchen
ERC
Friedrich-Baur Stiftung