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Hovanec, J.* ; Siemiatycki, J.* ; Conway, D.I.* ; Olsson, A.* ; Guénel, P.* ; Luce, D.* ; Joeckel, K.* ; Pohlabeln, H.* ; Ahrens, W.* ; Karrasch, S. ; Wichmann, H.-E. ; Gustavsson, P.* ; Consonni, D.* ; Merletti, F.* ; Richiardi, L.* ; Simonato, L.* ; Fortes, C.* ; Parent, M.* ; McLaughlin, J.R.* ; Demers, P.* ; Landi, M.T.* ; Caporaso, N.* ; Fernandez-Tardon, G.* ; Zaridze, D.* ; Swiatkowska, B.* ; Pándics, T.* ; Lissowska, J.* ; Fabianova, E.* ; Field, J.K.* ; Mates, D.* ; Bencko, V.* ; Foretova, L.* ; Janout, V.* ; Kromhout, H.* ; Vermeulen, R.* ; Boffetta, P.* ; Straif, K.* ; Schüz, J.* ; Casjens, S.* ; Pesch, B.* ; Bruening, T.* ; Behrens, T.*

Application of two job indices for general occupational demands in a pooled analysis of case-control studies on lung cancer.

Scand. J. Work Environ. Health 47, 475-481 (2021)
Postprint Forschungsdaten DOI PMC
Open Access Gold (Paid Option)
Creative Commons Lizenzvertrag
Objectives We investigated general job demands as a risk factor for lung cancer as well as their role in the association between occupational prestige and lung cancer.Methods In 13 case-control studies on lung cancer, as part of the international SYNERGY project, we applied indices for physical (PHI) and psychosocial (PSI) job demands - each with four categories (high to low). We estimated odds ratios (OR) and 95% confidence intervals (CI) for lung cancer by unconditional logistic regression, separately for men and women and adjusted for study centre, age, smoking behavior, and former employment in occupations with potential exposure to carcinogens. Further, we investigated, whether higher risks among men with low occupational prestige (Treiman's Standard International Occupational Prestige Scale) were affected by adjustment for the job indices.Results In 30 355 men and 7371 women, we found increased risks (OR) for lung cancer with high relative to low job demands in both men [PHI 1.74 (95% CI 1.56-1.93), PSI 1.33 (95% CI 1.17-1.51)] and women [PHI 1.62 (95% CI 1.24-2.11), PSI 1.31 (95% CI 1.09-1.56)]. OR for lung cancer among men with low occupational prestige were slightly reduced when adjusting for PHI [low versus high prestige OR from 1.44 (95% CI 1.32-1.58) to 1.30 (95% CI 1.17-1.45)], but not PSI.Conclusions Higher physical job demands were associated with increased risks of lung cancer, while associations for higher psychosocial demands were less strong. In contrast to physical demands, psychosocial demands did not contribute to clarify the association of occupational prestige and lung cancer.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Job Index ; Psychosocial ; Smoking ; Social Prestige ; Tumor Subtype; Risk
ISSN (print) / ISBN 0355-3140
e-ISSN 1795-990X
Zeitschrift Scandinavian Journal of Work, Environment & Health
Quellenangaben Band: 47, Heft: 6, Seiten: 475-481 Artikelnummer: , Supplement: ,
Verlag Nordic Association of Occupational Safety and Health (NOROSH)
Verlagsort Topeliuksenkatu 41a, Sf-00250 Helsinki, Finland
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology (EPI)
Förderungen German Social Accident Insurance