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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
When should I eat: A circadian view on food intake and metabolic regulation.
Acta Physiol. 237:e13936 (2023)
The circadian clock is a hierarchical timing system regulating most physiological and behavioral functions with a period of approximately 24 hours in humans and other mammalian species. The circadian clock drives daily eating rhythms that, in turn, reinforce the circadian clock network itself to anticipate and orchestrate metabolic responses to food intake. Eating is tightly interconnected with the circadian clock and recent evidence shows that the timing of meals is crucial for the control of appetite and metabolic regulation. Obesity results from combined long-term dysregulation in food intake (homeostatic and hedonic circuits), energy expenditure, and energy storage. Increasing evidence supports that the loss of synchrony of daily rhythms significantly impairs metabolic homeostasis and is associated with obesity. This review presents an overview of mechanisms regulating food intake (homeostatic/hedonic) and focuses on the crucial role of the circadian clock on the metabolic response to eating, thus providing a fundamental research axis to maintain a healthy eating behavior.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
Circadian Misalignment ; Homeostatic/hedonic Food Intake ; Mammalian Circadian Clock ; Metabolism ; Obesity; Randomized Controlled-trial; Fasting Lipid Profiles; Meal Frequency; Gene-expression; Caloric-intake; Weight-loss; Glucocorticoid-receptor; Anticipatory Activity; Macronutrient Intake; Insulin Sensitivity
ISSN (print) / ISBN
1748-1708
e-ISSN
1748-1716
Zeitschrift
Acta Physiologica
Quellenangaben
Band: 237,
Heft: 3,
Artikelnummer: e13936
Verlag
Wiley
Verlagsort
Hoboken
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Diabetes and Endocrinology (IDE)
Institute of Diabetes and Cancer (IDC)
Institute of Diabetes and Cancer (IDC)