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Schultes, B.* ; Ernst, B.* ; Hallschmid, M. ; Bueter, M.* ; Meyhöfer, S.M.*

The ‘Behavioral Balance Model’: A new perspective on the aetiology and therapy of obesity.

Diabetes Obes. Metab. 25, 3444-3452 (2023)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Obesity is a debilitating disease of global proportions that necessitates refined, concept-driven therapeutic approaches. Policy makers, the public and even health care professionals, but also individuals with obesity harbour many misconceptions regarding this disease, which leads to prejudice, negative attitudes, stigmatization, discrimination, self-blame, and failure to provide and finance adequate medical care. Decades of intensive, successful scientific research on obesity have only had a very limited effect on this predicament. We propose a science-based, easy-to-understand conceptual model that synthesizes the complex pathogenesis of obesity including biological, psychological, social, economic and environmental aspects with the aim to explain and communicate better the nature of obesity and currently available therapeutic modalities. According to our integrative ‘Behavioral Balance Model’, ‘top-down cognitive control’ strategies are implemented (often with limited success) to counterbalance the increased ‘bottom-up drive’ to gain weight, which is triggered by biological, psycho-social and environmental mechanisms in people with obesity. Besides offering a deeper understanding of obesity, the model also highlights why there is a strong need for multimodal therapeutic approaches that may not only increase top-down control but also reduce a pathologically increased bottom-up drive.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Korrespondenzautor
Schlagwörter Antidiabetic Drug ; Appetite Control ; Bariatric Surgery ; Glp-1 Analogue ; Obesity Therapy ; Weight Control; Eating Behavior; Weight-loss; Food-intake; Brain; Consequences; Disorders; Outcomes; Health; Stigma; Reward
ISSN (print) / ISBN 1462-8902
e-ISSN 1463-1326
Zeitschrift Diabetes, Obesity and Metabolism
Quellenangaben Band: 25, Heft: 12, Seiten: 3444-3452 Artikelnummer: , Supplement: ,
Verlag Wiley
Verlagsort 111 River St, Hoboken 07030-5774, Nj Usa
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Diabetes Research and Metabolic Diseases (IDM)
Förderungen German Federal Ministry of Education and Research (BMBF)
Eli Lilly
Novo Nordisk
Swiss National Science Foundation (SNF)
German Research Foundation (DFG)