PuSH - Publikationsserver des Helmholtz Zentrums München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Fritsche, A.

Einfache Einteilung der Subtypen des Diabetes in der Praxis.Ein Kommentar.

Simple diabetes subtype classification in clinical practice: A commentary.

Diabetologie 19, 112-116 (2023)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Background: Diabetes mellitus is a complex disease with different pathophysiological causes. Research in recent years has described various pheno- and genotypically defined subgroups for both prediabetes and diabetes. Question: For everyday clinical practice, it is essential to recognize the different phenotypes. It is proposed to do this using a simple measurement of endogenous insulin secretion. Materials and methods: The fasting C‑peptide/glucose ratio (CGR) can be used to estimate endogenous insulin secretion. A prerequisite for this is preserved kidney function (GFR > 50 ml/min/1.73 m2). Results: Autoimmune diabetes and its subtypes can be recognized by a low C‑peptide/glucose ratio, representing a lack of endogenous insulin secretion. A low CGR also describes severe insulin-deficient diabetes (SIDD). In contrast, severe insulin-resistant diabetes (SIRD) is characterized by a high CGR, which is equivalent to insulin hypersecretion. Conclusion: The C‑peptide/glucose ratio allows a simple assessment of different pathophysiological forms of diabetes. Importantly, it can also provide additional information on the need for insulin therapy.
Impact Factor
Scopus SNIP
Altmetric
0.400
0.000
Tags
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern

Zusatzinfos bearbeiten
Eigene Tags bearbeiten
Privat
Eigene Anmerkung bearbeiten
Privat
Auf Publikationslisten für
Homepage nicht anzeigen
Als besondere Publikation
markieren
Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter C‑peptide ; Diabetes Classification ; Glucose Metabolism Disorders ; Insulin Secretion ; Insulin, Therapy
Sprache deutsch
Veröffentlichungsjahr 2023
HGF-Berichtsjahr 2023
ISSN (print) / ISBN 2731-7447
e-ISSN 2731-7455
Zeitschrift Diabetologie, Die
Quellenangaben Band: 19, Heft: 2, Seiten: 112-116 Artikelnummer: , Supplement: ,
Verlag Springer
Verlagsort Tiergartenstrasse 17, D-69121 Heidelberg, Germany
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Diabetes Research and Metabolic Diseases (IDM)
POF Topic(s) 90000 - German Center for Diabetes Research
Forschungsfeld(er) Helmholtz Diabetes Center
PSP-Element(e) G-502400-001
DOI 10.1007/s11428-022-00992-4
WOS ID 000924165300001
Scopus ID 85164948313
Erfassungsdatum 2023-12-06
[➜Korrektur melden]