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Lagogiannis, I.* ; Meissen, F.* ; Kaissis, G. ; Rueckert, D.*

Unsupervised pathology detection: A deep dive Into the state of the art.

IEEE Trans. Med. Imaging 43, 241-252 (2024)
Postprint DOI PMC
Open Access Green
Deep unsupervised approaches are gathering increased attention for applications such as pathology detection and segmentation in medical images since they promise to alleviate the need for large labeled datasets and are more generalizable than their supervised counterparts in detecting any kind of rare pathology. As the Unsupervised Anomaly Detection (UAD) literature continuously grows and new paradigms emerge, it is vital to continuously evaluate and benchmark new methods in a common framework, in order to reassess the state-of-the-art (SOTA) and identify promising research directions. To this end, we evaluate a diverse selection of cutting-edge UAD methods on multiple medical datasets, comparing them against the established SOTA in UAD for brain MRI. Our experiments demonstrate that newly developed feature-modeling methods from the industrial and medical literature achieve increased performance compared to previous work and set the new SOTA in a variety of modalities and datasets. Additionally, we show that such methods are capable of benefiting from recently developed self-supervised pre-training algorithms, further increasing their performance. Finally, we perform a series of experiments in order to gain further insights into some unique characteristics of selected models and datasets. Our code can be found under https://github.com/iolag/UPD_study/.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Anomaly detection; Medical diagnostic imaging; Image reconstruction; Pathology; Feature extraction; Training; Task analysis; Unsupervised; anomaly; detection; segmentation; medical; comparative; generative; image-reconstruction; feature-modeling; self-supervised; pre-training; Anomaly Detection; Segmentation
Sprache englisch
Veröffentlichungsjahr 2024
HGF-Berichtsjahr 2024
ISSN (print) / ISBN 0278-0062
e-ISSN 1558-254X
Zeitschrift IEEE Transactions on Medical Imaging
Quellenangaben Band: 43, Heft: 1, Seiten: 241-252 Artikelnummer: , Supplement: ,
Verlag Institute of Electrical and Electronics Engineers (IEEE)
Verlagsort New York, NY [u.a.]
Begutachtungsstatus Peer reviewed
Institut(e) Institute for Machine Learning in Biomed Imaging (IML)
POF Topic(s) 30205 - Bioengineering and Digital Health
Forschungsfeld(er) Enabling and Novel Technologies
PSP-Element(e) G-507100-001
Förderungen Munich Center for Machine Learning
DOI 10.1109/TMI.2023.3298093
WOS ID 001158081600010
PubMed ID 37506004
Erfassungsdatum 2024-04-25
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