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Stefani, A.* ; Tang, Q.* ; Clemens, S.* ; DelRosso, L.M.* ; García-Borreguero, D.* ; Ferri, R.* ; Frauscher, B.* ; Holzknecht, E.* ; Provini, F.* ; Schormair, B. ; Winkelman, J.W.* ; Högl, B.*

Sleep related movement disorders: What's new and changing clinical practice.

J. Sleep Res., DOI: 10.1111/jsr.70210:e70210 (2025)
Verlagsversion DOI PMC
Open Access Hybrid
Creative Commons Lizenzvertrag
Restless legs syndrome (RLS) is a common sensorimotor disorder, and the most common sleep-related movement disorder with a prevalence of up to 15% in the European and US population. This review addresses key aspects of RLS, focusing on novel data that have or will likely have an impact on clinical practice. These include novel insights into pathophysiology and motor activity during sleep, with a key focus on implications for RLS treatment. Along this line, we discuss the problem of augmentation before introducing new treatment paradigms and insights into new drug targets from genetics. Besides RLS, restless sleep disorder, neck myoclonus, fragmentary myoclonus, propriospinal myoclonus at the wake-sleep transition, and facio-mandibular myoclonus are discussed. This review provides an overview of the most recent insights into sleep-related movement disorders, and of how they are changing clinical practice.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Rls ; Rsdlmm ; Large Muscle Group Movements ; Restless Legs Syndrome ; Restless Sleep Disorder
Sprache englisch
Veröffentlichungsjahr 2025
HGF-Berichtsjahr 2025
ISSN (print) / ISBN 0962-1105
e-ISSN 0962-1105
Zeitschrift Journal of Sleep Research
Quellenangaben Band: , Heft: , Seiten: , Artikelnummer: e70210 Supplement: ,
Verlag Wiley
Verlagsort Oxford
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Neurogenomics (ING)
POF Topic(s) 30205 - Bioengineering and Digital Health
Forschungsfeld(er) Genetics and Epidemiology
PSP-Element(e) G-503200-001
DOI 10.1111/jsr.70210
Scopus ID 105017750380
PubMed ID 41041830
Erfassungsdatum 2025-10-24
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