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Loewenstein, Y.* ; Raimondo, D.* ; Redfern, O.C.* ; Watson, J.* ; Frishman, D. ; Linial, M.* ; Orengo, C.* ; Thornton, J.* ; Tramontano, A.*

Protein function annotation by homology-based inference.

Genome Biol. 10:207 (2009)
Publ. Version/Full Text Volltext DOI PMC
Open Access Gold
With many genomes now sequenced, computational annotation methods to characterize genes and proteins from their sequence are increasingly important. The BioSapiens Network has developed tools to address all stages of this process, and here we review progress in the automated prediction of protein function based on protein sequence and structure.
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Publication type Article: Journal article
Document type Review
Corresponding Author
Keywords structure allignment; domain interactions; interacting proteins; hierarchical-classification; evolutionary conservation; structural genomics; 3D structure; database; prediction; sites
ISSN (print) / ISBN 1474-760X
e-ISSN 1465-6906
Journal Genome Biology
Quellenangaben Volume: 10, Issue: 2, Pages: , Article Number: 207 Supplement: ,
Publisher BioMed Central
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Bioinformatics and Systems Biology (IBIS)