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Chen, S.Y.* ; Wu, C.F.* ; Lee, J.H.* ; Hoffmann, B.* ; Peters, A. ; Brunekreef, B.* ; Chu, D.C.* ; Chan, C.C.*

Associations between long-term air pollutant exposures and blood pressure in elderly residents of Taipei city: A cross-sectional study.

Environ. Health Perspect. 123, 779-784 (2015)
Publ. Version/Full Text Supplement DOI
Background: Limited information is available regarding long-term effects of air pollution on blood pressure (BP) and hypertension. Objective: We studied whether 1-year exposures to particulate matter (PM) and nitrogen oxides (NOx) were correlated with BP and hypertension in the elderly. Methods: We analyzed cross-sectional data from 27,752 Taipei City residents > 65 years of age who participated in a health examination program in 2009. Land-use regression models were used to estimate participants’ 1-year exposures to particulate matter with aerodynamic diameter ≤ 10 μm (PM10), coarse particles (PM2.5–10), fine particles (≤ 2.5 μm; PM2.5), PM2.5absorbance, NOx, and nitrogen dioxide (NO2). Generalized linear regressions and logistic regressions were used to examine the association between air pollution and BP and hypertension, respectively. Results: Diastolic BP was associated with 1-year exposures to air pollution, with estimates of 0.73 [95% confidence interval (CI): 0.44, 1.03], 0.46 (95% CI: 0.30, 0.63), 0.62 (95% CI: 0.24, 0.99), 0.34 (95% CI: 0.19, 0.50), and 0.65 (95% CI: 0.44, 0.85) mmHg for PM10 (10 μg/m3), PM2.5–10 (5 μg/m3), PM2.5 absorbance (10–5/m), NOx (20 μg/m3), and NO2 (10 μg/m3), respectively. PM2.5 was not associated with diastolic BP, and none of the air pollutants was associated with systolic BP. Associations of diastolic BP with PM10 and PM2.5 absorbance were stronger among participants with hypertension, diabetes, or a body mass index ≥ 25 kg/m2 than among participants without these conditions. One-year air pollution exposures were not associated with hypertension. Conclusions: One-year exposures to PM10, PM2.5-10, PM2.5 absorbance, and NOx were associated with higher diastolic BP in elderly residents of Taipei.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0091-6765
e-ISSN 1552-9924
Journal Environmental Health Perspectives
Quellenangaben Volume: 123, Issue: 8, Pages: 779-784 Article Number: , Supplement: ,
Publisher Research Triangle Park
Publishing Place NC [u.a.]
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology II (EPI2)