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Exercise and diabetes: Relevance and causes for response variability.

Endocrine 51, 390-401 (2016)
Publ. Version/Full Text Postprint DOI PMC
Open Access Gold (Paid Option)
Creative Commons Lizenzvertrag
Exercise as a key prevention strategy for diabetes and obesity is commonly accepted and recommended throughout the world. Unfortunately, not all individuals profit to the same extent, some exhibit exercise resistance. This phenomenon of non-response to exercise is found for several endpoints, including glucose tolerance and insulin sensitivity. Since these non-responders are of notable quantity, there is the need to understand the underlying mechanisms and to identify predictors of response. This displays the basis to develop personalized training intervention regimes. In this review, we summarize the current knowledge on response variability, with focus on human studies and improvement of glucose homeostasis as outcome.
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Publication type Article: Journal article
Document type Review
Corresponding Author
Keywords Adverse Response To Exercise ; Exercise Resistance ; Glucose Homeostasis ; Glucose Tolerance ; Insulin Sensitivity ; Lifestyle Intervention ; Non-response; Life-style Intervention; Human Skeletal-muscle; Subcutaneous Adipose-tissue; Impaired Glucose-tolerance; Risk Reduction Intervention; High Liver Fat; Insulin Sensitivity; Metabolic Syndrome; Physical-activity; Heritage Family
ISSN (print) / ISBN 1355-008X
e-ISSN 1559-0100
Journal Endocrine
Quellenangaben Volume: 51, Issue: 3, Pages: 390-401 Article Number: , Supplement: ,
Publisher Springer
Publishing Place Totowa, NJ
Non-patent literature Publications
Reviewing status Peer reviewed