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Open Access Green as soon as Postprint is submitted to ZB.
Viral hepatitis: The bumpy road to animal models for HBV infection.
Nat. Rev. Gastroenterol. Hepatol. 14, 327-328 (2017)
Cell culture infection models help to develop antiviral agents, but animal models are required to understand complex virus-host interactions and the development of immune therapies. Although identification of the HBV uptake receptor enabled establishing cell lines that replicate HBV from its natural transcription template, animal models supporting the full HBV life cycle are still lacking.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Hepatitis-b-virus; Mice; Replication; Leads
ISSN (print) / ISBN
1759-5045
e-ISSN
1759-5053
Quellenangaben
Volume: 14,
Issue: 6,
Pages: 327-328
Publisher
Nature Publishing Group
Publishing Place
New York
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Virology (VIRO)