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Viral hepatitis: The bumpy road to animal models for HBV infection.
Nat. Rev. Gastroenterol. Hepatol. 14, 327-328 (2017)
Cell culture infection models help to develop antiviral agents, but animal models are required to understand complex virus-host interactions and the development of immune therapies. Although identification of the HBV uptake receptor enabled establishing cell lines that replicate HBV from its natural transcription template, animal models supporting the full HBV life cycle are still lacking.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Hepatitis-b-virus; Mice; Replication; Leads
Language
english
Publication Year
2017
HGF-reported in Year
2017
ISSN (print) / ISBN
1759-5045
e-ISSN
1759-5053
Quellenangaben
Volume: 14,
Issue: 6,
Pages: 327-328
Publisher
Nature Publishing Group
Publishing Place
New York
Reviewing status
Peer reviewed
Institute(s)
Institute of Virology (VIRO)
POF-Topic(s)
30203 - Molecular Targets and Therapies
Research field(s)
Immune Response and Infection
PSP Element(s)
G-502700-003
PubMed ID
28400622
WOS ID
WOS:000402116200002
Scopus ID
85017453274
Erfassungsdatum
2017-06-26