Combined pulse-echo ultrasound and multispectral optoacoustic tomography with a multi-segment detector array.
IEEE Trans. Med. Imaging 36, 2129-2137 (2017)
The high complementarity of ultrasonography and optoacoustic tomography has prompted the development of combined approaches that utilize the same transducer array for detecting both optoacoustic and pulse-echo ultrasound responses from tissues. Yet, due to the fundamentally different physical contrast and image formation mechanisms, the development of detection technology optimally suited for image acquisition in both modalities remains a major challenge. Herein, we introduce a multi-segment detector array approach incorporating array segments of linear and concave geometry to optimally support both ultrasound and optoacoustic image acquisition. The various image rendering strategies are tested and optimized in numerical simulations and calibrated tissue-mimicking phantom experiments. We subsequently demonstrate real-time hybrid optoacoustic ultrasound (OPUS) image acquisition in a healthy volunteer. The new approach enables the acquisition of highquality anatomical data by both modalities complemented by functional information on blood oxygenation status provided by the multispectral optoacoustic tomography.
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Publication type
Article: Journal article
Document type
Scientific Article
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Keywords
Anatomical Structure ; Photoacoustic Imaging ; Ultrasonography ; Ultrasonic Transducers; Hand-held Probe; In-vivo; Cardiovascular Dynamics; Coherence Tomography; System; Vasculature; Microscopy; Inversion; Perfusion; Cancer
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Language
english
Publication Year
2017
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2017
ISSN (print) / ISBN
0278-0062
e-ISSN
1558-254X
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Volume: 36,
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Pages: 2129-2137
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Institute of Electrical and Electronics Engineers (IEEE)
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New York, NY [u.a.]
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Reviewing status
Peer reviewed
POF-Topic(s)
30205 - Bioengineering and Digital Health
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-505590-001
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Erfassungsdatum
2017-06-23