PuSH - Publication Server of Helmholtz Zentrum München

Mercep, E. ; Dean-Ben, X.L. ; Razansky, D.

Combined pulse-echo ultrasound and multispectral optoacoustic tomography with a multi-segment detector array.

IEEE Trans. Med. Imaging 36, 2129-2137 (2017)
Postprint DOI PMC
Open Access Green
The high complementarity of ultrasonography and optoacoustic tomography has prompted the development of combined approaches that utilize the same transducer array for detecting both optoacoustic and pulse-echo ultrasound responses from tissues. Yet, due to the fundamentally different physical contrast and image formation mechanisms, the development of detection technology optimally suited for image acquisition in both modalities remains a major challenge. Herein, we introduce a multi-segment detector array approach incorporating array segments of linear and concave geometry to optimally support both ultrasound and optoacoustic image acquisition. The various image rendering strategies are tested and optimized in numerical simulations and calibrated tissue-mimicking phantom experiments. We subsequently demonstrate real-time hybrid optoacoustic ultrasound (OPUS) image acquisition in a healthy volunteer. The new approach enables the acquisition of highquality anatomical data by both modalities complemented by functional information on blood oxygenation status provided by the multispectral optoacoustic tomography.
Altmetric
Additional Metrics?
[➜Log in]
Edit extra informations Login
Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Anatomical Structure ; Photoacoustic Imaging ; Ultrasonography ; Ultrasonic Transducers; Hand-held Probe; In-vivo; Cardiovascular Dynamics; Coherence Tomography; System; Vasculature; Microscopy; Inversion; Perfusion; Cancer
ISSN (print) / ISBN 0278-0062
e-ISSN 1558-254X
Journal IEEE Transactions on Medical Imaging
Quellenangaben Volume: 36, Issue: 10, Pages: 2129-2137 Article Number: , Supplement: ,
Publisher Institute of Electrical and Electronics Engineers (IEEE)
Publishing Place New York, NY [u.a.]
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Biological and Medical Imaging (IBMI)