PuSH - Publication Server of Helmholtz Zentrum München: The relationship between breast milk leptin and adiponectin with child body composition from 3 to 5 years: A follow-up study.

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Meyer, D.M.* ; Brei, C.* ; Stecher, L.* ; Much, D. ; Brunner, S.* ; Hauner, H.*

The relationship between breast milk leptin and adiponectin with child body composition from 3 to 5 years: A follow-up study.

Pediatr. Obes. 12, 1, 125-129 (2017)

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BackgroundResearch indicates that breast milk contains bioactive components that influence metabolism in infancy and may play a role in the prevention of obesity in early childhood. In our initial study, 147 breastfeeding mother/child pairs were followed from birth to 2 years of age to examine the relationship between breast milk leptin and total adiponectin (collected at 6 weeks and 4 months postpartum) and infant body composition. Higher breast milk total adiponectin was related to greater fat mass and weight gain in children at 1 and 2 years of age, whereas leptin showed no association. Objectives/MethodsIn this follow-up, we examined the relationship between both adipokines and children's body weight, body mass index percentiles, sum of four skin-folds, percentage of body fat, fat mass and lean body mass at 3, 4 and 5 years of age. ResultsBreast milk adipokines were largely unrelated to child anthropometric measures. ConclusionOur results do not provide significant evidence that breast milk adipokines can predict adiposity in preschool children.

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