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Open Access Green as soon as Postprint is submitted to ZB.
Glial control of neurogenesis.
Curr. Opin. Neurobiol. 47, 188-195 (2017)
Glial cells are central components of all neurogenic niches in the embryonic as well as in the adult central nervous system. While neural stem cells (NSCs) themselves exhibit glial features the behavior of NSCs is also strongly influenced by niche glial cells. Recently, studies have begun to uncover a large variety of glial cell-extrinsic as well as intrinsic factors that play crucial roles in the control of NSCs and the regulation of the cellular output from the neurogenic niches. In this review, we focus on mechanisms underlying the formation of adult NSCs by embryonic radial glia cells, discuss the influence of niche glia cells on adult NSCs and examine how the neurogenic potential of glial cells is controlled.
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Publication type
Article: Journal article
Document type
Review
Keywords
Neural Stem-cells; Adult Hippocampal Neurogenesis; In-vitro; Subventricular Zone; Subependymal Zone; Embryonic Origin; Reactive Gliosis; Ependymal Cells; Olfactory-bulb; Injured Brain
ISSN (print) / ISBN
0959-4388
e-ISSN
1873-6882
Journal
Current Opinion in Neurobiology
Quellenangaben
Volume: 47,
Pages: 188-195
Publisher
Elsevier
Publishing Place
London
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Stem Cell Research (ISF)