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Aglas, L.* ; Gilles, S. ; Bauer, R.* ; Huber, S.* ; Araujo, G.R.* ; Mueller, G.* ; Scheiblhofer, S.* ; Amisi, M. ; Dang, H.H.* ; Briza, P.* ; Bohle, B.* ; Horejs-Hoeck, J.* ; Traidl-Hoffmann, C. ; Ferreira, F.*

Context matters: T(H)2 polarization resulting from pollen composition and not from protein-intrinsic allergenicity.

J. Allergy Clin. Immunol. 142, 984-987.e6 (2018)

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In contrast to the pollen context, the major allergen Bet v 1 alone is not responsible for Th2 polarization in allergic sensitization. These findings are highly relevant for birch pollen allergy prophylaxis.

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Publication type Article: Journal article

Document type Scientific Article

Keywords Allergic Sensitization ; Bet V 1 ; Lps ; Tlr4 ; Th2 Polarization ; Allergenicity ; Allergy Prophylaxis ; Birch Pollen ; Pollen Extract; Allergic Contact-dermatitis; Genome-wide Association; Antigen-presenting Cells; T-cells; Collaborative Cross; Rapid Identification; Molecular-mechanisms; Immune-responses; Dendritic Cells; Transgenic Mice

ISSN (print) / ISBN 0091-6749

e-ISSN 1097-6825

Journal The journal of allergy and clinical immunology

Quellenangaben Volume: 142, Issue: 3, Pages: 984-987.e6

Publisher Elsevier

Publishing Place Amsterdam [u.a.]

Reviewing status Peer reviewed

Institute(s) Institute of Environmental Medicine (IEM)