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Kyriakou, E. ; Kostagianni, A.D.* ; Kellici, T.F.* ; Giannopoulou, E.A.* ; Siatis, K.E.* ; Sayyad, N.* ; Kalofonos, H.P.* ; Mavromoustakos, T.* ; Stamatis, H.* ; Tzakos, A.G.*

Three regioselectively acylated flavonoid aglycone derivatives in equimolar yield at one blow.

ChemistrySelect 3, 5207-5211 (2018)

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	Open Access Green

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A simple and time‐effective chemoenzymatic process to obtain three regioselective acylated quercetin analogues in a 1:1:1 ratio in one pot is described. This process overcomes the inherent scaffold intricacy and synthetic complexity of quercetin. Cell proliferation experiments in three breast cancers cell lines pinpoint the high potency of the generated compounds.

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Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

Keywords Biocatalysis ; Cancer ; Quercetin ; In Silico Studies ; Nmr Experiments ; Regioselectivity

ISSN (print) / ISBN 2365-6549

e-ISSN 2365-6549

Journal ChemistrySelect

Quellenangaben Volume: 3, Issue: 18, Pages: 5207-5211

Publisher Wiley

Publishing Place Weinheim

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute of Structural Biology (STB)