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Conzade, R. ; Grant, R.* ; Malik, M.R.* ; Elkholy, A.* ; Elhakim, M.* ; Samhouri, D.* ; Ben Embarek, P.K.* ; Van Kerkhove, M.D.*

Reported direct and indirect contact with dromedary camels among laboratory-confirmed MERS-CoV cases .

Viruses 10:425 (2018)
Publ. Version/Full Text Postprint DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Dromedary camels (Camelus dromedarius) are now known to be the vertebrate animal reservoir that intermittently transmits the Middle East respiratory syndrome coronavirus (MERS-CoV) to humans. Yet, details as to the specific mechanism(s) of zoonotic transmission from dromedaries to humans remain unclear. The aim of this study was to describe direct and indirect contact with dromedaries among all cases, and then separately for primary, non-primary, and unclassified cases of laboratory-confirmed MERS-CoV reported to the World Health Organization (WHO) between 1 January 2015 and 13 April 2018. We present any reported dromedary contact: direct, indirect, and type of indirect contact. Of all 1125 laboratory-confirmed MERS-CoV cases reported to WHO during the time period, there were 348 (30.9%) primary cases, 455 (40.4%) non-primary cases, and 322 (28.6%) unclassified cases. Among primary cases, 191 (54.9%) reported contact with dromedaries: 164 (47.1%) reported direct contact, 155 (44.5%) reported indirect contact. Five (1.1%) non-primary cases also reported contact with dromedaries. Overall, unpasteurized milk was the most frequent type of dromedary product consumed. Among cases for whom exposure was systematically collected and reported to WHO, contact with dromedaries or dromedary products has played an important role in zoonotic transmission.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Mers-cov ; Dromedary Camels ; Zoonotic Transmission; Respiratory Syndrome Coronavirus; To-human Transmission; Saudi-arabia; Risk-factors; Infected Camels; Abu-dhabi; Africa; Antibodies; Emergence; Outbreak
ISSN (print) / ISBN 1999-4915
e-ISSN 1999-4915
Journal Viruses
Quellenangaben Volume: 10, Issue: 8, Pages: , Article Number: 425 Supplement: ,
Publisher MDPI
Publishing Place St Alban-anlage 66, Ch-4052 Basel, Switzerland
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology II (EPI2)