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Carsin, A.E.* ; Fuertes, E.* ; Schaffner, E.* ; Jarvis, D.* ; Antò, J.M.* ; Heinrich, J. ; Bellisario, V.* ; Svanes, C.* ; Keidel, D.* ; Imboden, M.* ; Weyler, J.* ; Nowak, D.* ; Martinez-Moratalla, J.* ; Gullón, J.A.* ; Sanchez Ramos, J.L.* ; Caviezel, S.* ; Beckmeyer-Borowko, A.* ; Raherison, C.* ; Pin, I.* ; Demoly, P.* ; Cerveri, I.* ; Accordini, S.* ; Gislason, T.* ; Toren, K.* ; Forsberg, B.* ; Janson, C.* ; Jogi, R.* ; Emtner, M.* ; Gómez Real, F.* ; Raza, W.* ; Leynaert, B.* ; Pascual, S.* ; Guerra, S.* ; Dharmage, S.C.* ; Probst-Hensch, N.* ; Garcia-Aymerich, J.*

Restrictive spirometry pattern is associated with low physical activity levels. A population based international study.

Respir. Med. 146, 116-123 (2019)
Publ. Version/Full Text Research data DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Introduction: Restrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortality prognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and with normal spirometry.Methods: Restrictive spirometry pattern was defined as a having post-bronchodilator FEV1/FVC >= Lower Limit of Normal and a FVC< 80% predicted in two population-based studies (ECRHS-III and SAPALDIA3). Physical activity was measured using the International Physical Activity Questionnaire. The odds of having low physical activity (< 1st study-specific tertile) was evaluated using adjusted logistic regression models.Results: Subjects with a restrictive spirometry pattern (n = 280/4721 in ECRHS, n = 143/3570 in SAPALDIA) reported lower levels of physical activity than those with normal spirometry (median of 1770 vs 2253 MET.min/week in ECRHS, and 3519 vs 3945 MET.min/week in SAPALDIA). Subjects with a restrictive spirometry pattern were more likely to report low physical activity (meta-analysis odds ratio: 1.41 [95% CI 1.07-1.86]) than those with a normal spirometry. Obesity, respiratory symptoms, co-morbidities and previous physical activity levels did not fully explain this finding.Conclusion: Adults with a restrictive spirometry pattern were more likely to report low levels of physical activity than those with normal spirometry. These results highlight the need to identify and act on this understudied but prevalent condition.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Restrictive Spirometry Pattern ; Body Mass Index ; Epidemiology ; Lung Function ; Physical Activity; Lung-function; Activity Questionnaire; National-health; Mortality; Disease; Impairment; Disorder; Events; Risk
Language english
Publication Year 2019
Prepublished in Year 2018
HGF-reported in Year 2018
ISSN (print) / ISBN 0954-6111
e-ISSN 1532-3064
Journal Respiratory Medicine
Quellenangaben Volume: 146, Issue: , Pages: 116-123 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place 32 Jamestown Rd, London Nw1 7by, England
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology (EPI)
POF-Topic(s) 30202 - Environmental Health
Research field(s) Genetics and Epidemiology
PSP Element(s) G-504000-008
DOI 10.1016/j.rmed.2018.11.017
WOS ID WOS:000456074000018
Scopus ID 85058942184
PubMed ID 30665509
Erfassungsdatum 2018-12-31
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