Twenty years of proteomics in radiation biology - a look back.
Int. J. Radiat. Biol. 98, 341-345 (2021)
PURPOSE: The aim of this article is to describe the technical development in proteomics during the last two decades with the focus on its use in radiation biology. It is written from a subjective point of view and aims not to be a scientific review of the subject. CONCLUSION: Proteomics is a fast developing technique and it has already contributed greatly to our understanding of biological mechanisms following radiation exposure. Novel proteomics approaches can be used in adequately designed cellular and animal experiments and above all in big clinical trials to investigate effects of ionizing radiation in the future.
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Publication type
Article: Journal article
Document type
Review
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Keywords
Word ; Endothelial Cells ; Ionizing Radiation ; Label-free Proteomics ; Radiation-induced Heart Disease; Ionizing-radiation; Protein Acetylation; Mass-spectrometry; Heart; Electrophoresis; Expression; Silac
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Language
english
Publication Year
2021
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2021
ISSN (print) / ISBN
0955-3002
e-ISSN
1362-3095
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Volume: 98,
Issue: 3,
Pages: 341-345
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Informa Healthcare
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2-4 Park Square, Milton Park, Abingdon Or14 4rn, Oxon, England
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Reviewing status
Peer reviewed
POF-Topic(s)
30203 - Molecular Targets and Therapies
30202 - Environmental Health
Research field(s)
Radiation Sciences
PSP Element(s)
G-501300-001
G-500200-001
Grants
Federal Ministry of Education and Research of Germany (BMBF)
Copyright
Erfassungsdatum
2021-07-28