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Twenty years of proteomics in radiation biology - a look back.

Int. J. Radiat. Biol. 98, 341-345 (2021)
Postprint DOI PMC
Open Access Green
PURPOSE: The aim of this article is to describe the technical development in proteomics during the last two decades with the focus on its use in radiation biology. It is written from a subjective point of view and aims not to be a scientific review of the subject. CONCLUSION: Proteomics is a fast developing technique and it has already contributed greatly to our understanding of biological mechanisms following radiation exposure. Novel proteomics approaches can be used in adequately designed cellular and animal experiments and above all in big clinical trials to investigate effects of ionizing radiation in the future.
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Publication type Article: Journal article
Document type Review
Keywords Word ; Endothelial Cells ; Ionizing Radiation ; Label-free Proteomics ; Radiation-induced Heart Disease; Ionizing-radiation; Protein Acetylation; Mass-spectrometry; Heart; Electrophoresis; Expression; Silac
Language english
Publication Year 2021
HGF-reported in Year 2021
ISSN (print) / ISBN 0955-3002
e-ISSN 1362-3095
Quellenangaben Volume: 98, Issue: 3, Pages: 341-345 Article Number: , Supplement: ,
Publisher Informa Healthcare
Publishing Place 2-4 Park Square, Milton Park, Abingdon Or14 4rn, Oxon, England
Reviewing status Peer reviewed
POF-Topic(s) 30203 - Molecular Targets and Therapies
30202 - Environmental Health
Research field(s) Radiation Sciences
PSP Element(s) G-501300-001
G-500200-001
Grants Federal Ministry of Education and Research of Germany (BMBF)
Scopus ID 85125291135
PubMed ID 34187298
Erfassungsdatum 2021-07-28