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Twenty years of proteomics in radiation biology - a look back.
Int. J. Radiat. Biol. 98, 341-345 (2021)
PURPOSE: The aim of this article is to describe the technical development in proteomics during the last two decades with the focus on its use in radiation biology. It is written from a subjective point of view and aims not to be a scientific review of the subject. CONCLUSION: Proteomics is a fast developing technique and it has already contributed greatly to our understanding of biological mechanisms following radiation exposure. Novel proteomics approaches can be used in adequately designed cellular and animal experiments and above all in big clinical trials to investigate effects of ionizing radiation in the future.
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Publication type
Article: Journal article
Document type
Review
Keywords
Word ; Endothelial Cells ; Ionizing Radiation ; Label-free Proteomics ; Radiation-induced Heart Disease; Ionizing-radiation; Protein Acetylation; Mass-spectrometry; Heart; Electrophoresis; Expression; Silac
ISSN (print) / ISBN
0955-3002
e-ISSN
1362-3095
Quellenangaben
Volume: 98,
Issue: 3,
Pages: 341-345
Publisher
Informa Healthcare
Publishing Place
2-4 Park Square, Milton Park, Abingdon Or14 4rn, Oxon, England
Non-patent literature
Publications
Reviewing status
Peer reviewed
Grants
Federal Ministry of Education and Research of Germany (BMBF)