PuSH - Publication Server of Helmholtz Zentrum München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Dai, E.* ; Chen, X.* ; Linkermann, A.* ; Jiang, X.* ; Kang, R.* ; Kagan, V.E.* ; Bayir, H.* ; Yang, W.S.* ; Garcia-Saez, A.J.* ; Ioannou, M.S.* ; Janowitz, T.* ; Ran, Q.* ; Gu, W.* ; Gan, B.* ; Krysko, D.V.* ; Zhu, X.* ; Wang, J.* ; Krautwald, S.* ; Toyokuni, S.* ; Xie, Y.* ; Greten, F.R.* ; Yi, Q.* ; Schick, J. ; Liu, J.* ; Gabrilovich, D.I.* ; Zeh, H.J.* ; Zhang, D.D.* ; Yang, M.* ; Iovanna, J.L.* ; Kopf, M.* ; Adolph, T.E.* ; Chi, J.T.* ; Li, C.* ; Ichijo, H.* ; Karin, M.* ; Sankaran, V.G.* ; Zou, W.* ; Galluzzi, L.* ; Bush, A.I.* ; Li, B.* ; Melino, G.* ; Baehrecke, E.H.* ; Lotze, M.T.* ; Klionsky, D.J.* ; Stockwell, B.R.* ; Kroemer, G.* ; Tang, D.*

A guideline on the molecular ecosystem regulating ferroptosis.

Nat. Cell Biol., DOI: 10.1038/s41556-024-01360-8 (2024)
Postprint DOI PMC
Open Access Green
Ferroptosis, an intricately regulated form of cell death characterized by uncontrolled lipid peroxidation, has garnered substantial interest since this term was first coined in 2012. Recent years have witnessed remarkable progress in elucidating the detailed molecular mechanisms that govern ferroptosis induction and defence, with particular emphasis on the roles of heterogeneity and plasticity. In this Review, we discuss the molecular ecosystem of ferroptosis, with implications that may inform and enable safe and effective therapeutic strategies across a broad spectrum of diseases.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Altmetric
17.300
0.000
2
Tags
Annotations
Special Publikation
Hide on homepage

Edit extra information
Edit own tags
Private
Edit own annotation
Private
Hide on publication lists
on hompage
Mark as special
publikation
Publication type Article: Journal article
Document type Review
Keywords Cell-death; Lipid-peroxidation; Promotes Ferroptosis; Cancer-cells; Gpx4; Protects; Stress; Susceptibility; Activation; Roles
Language english
Publication Year 2024
HGF-reported in Year 2024
ISSN (print) / ISBN 1465-7392
e-ISSN 1476-4679
Journal Nature Cell Biology
Publisher Nature Publishing Group
Publishing Place Heidelberger Platz 3, Berlin, 14197, Germany
Reviewing status Peer reviewed
Institute(s) Institute of Molecular Toxicology and Pharmacology (TOX)
POF-Topic(s) 30203 - Molecular Targets and Therapies
Research field(s) Enabling and Novel Technologies
PSP Element(s) G-505200-006
Grants US National Institutes of Health
DOI 10.1038/s41556-024-01360-8
WOS ID 001181829200004
Scopus ID 85186233911
PubMed ID 38424270
Erfassungsdatum 2024-04-29
[➜Report correction]