Long-term associations between ambient air pollution and self-perceived health status: Results from the population-based KORA-Fit study.
Int. J. Hyg. Environ. Health 264:114513 (2025)
BACKGROUND: Little is known about the association between air pollution and self-perceived health (including both health-related quality of life [HRQoL] and self-rated health [SRH]). The aim of this study was therefore to explore whether long-term air pollution exposure is associated with worse self-perceived health, as measured by different tools. METHODS: We used a land-use regression model to determine the annual average levels of particulate matter with a diameter <10 μm (PM10), coarse particles (PMcoarse), fine particles (PM2.5), fine particle absorbances (PM2.5abs), particle number concentration (PNC), ozone (O3), nitrogen dioxide (NO2), and nitrogen oxide (NOX) for geocoded residential addresses (2014-2015). Questionnaires and face-to-face interviews were used to collect HRQoL (measured using the European Quality of Life 5 Dimensions [EQ-5D] index and the European Quality of Life Visual Analogue Scale [EQ-VAS]) and SRH indicators (measured through two survey questions) (2018-2019) from participants of the Cooperative Health Research in the Region of Augsburg (KORA)-Fit study in Germany. We explored associations via generalized additive models, multinomial logistic regression, and logistic regression. RESULTS: We included 2610 participants with a mean age of 64.0 years in this cross-sectional study, of which 1428 (54.7%) were female. Each interquartile range (IQR) increase in O3 was associated with a reduced EQ-5D index value (% change of mean points and 95% confidence interval: -0.91% [-1.76; -0.06]). The average EQ-VAS score declined between -1.57% and -0.96% with each IQR increase in PM10, PMcoarse, PM2.5abs, PNC, NO2, and NOX. These pollutants were associated with increased occurrence of poor SRH, with odds ratios ranging from 1.24 to 2.67. PM2.5abs was linked to a higher likelihood of reporting a worse comparative SRH (2.59 [1.12; 5.99]). Body mass index and self-perceived stress modified these associations. CONCLUSIONS: Long-term air pollution exposure was associated with poor self-perceived health, presenting as lower HRQoL and higher odds of poor SRH. Single-item indicators measuring self-perceived health status may work better than multi-dimensional indicators.
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Publication type
Article: Journal article
Document type
Scientific Article
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Keywords
Ambient Air Pollution ; Eq-vas ; Health-related Quality Of Life ; Self-perceived Health ; Self-rated Health; Quality-of-life; Use Regression-models; Rated Health; Exposure; Risk; Stress; Europe; Ozone; No2
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Language
english
Publication Year
2025
Prepublished in Year
2024
HGF-reported in Year
2024
ISSN (print) / ISBN
1438-4639
e-ISSN
1618-131X
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Volume: 264,
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Article Number: 114513
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Elsevier
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Amsterdam ; Boston, Mass. ; London ; New York, NY ; Oxford ; Paris ; Philadelphia, Pa. ; San Diego, Calif. ; St. Louis, Mo. ; München
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Peer reviewed
POF-Topic(s)
30202 - Environmental Health
Research field(s)
Genetics and Epidemiology
PSP Element(s)
G-504000-001
G-505300-001
G-504000-010
G-504090-001
Grants
China Scholarship Council
Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health
State of Bavaria
German Federal Ministry of Education and Research (BMBF)
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Erfassungsdatum
2025-01-08