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Mishima, E. ; O'Neill, T.J. ; Hoefig, K.P. ; Chen, D. ; Behrens, G. ; Henkelmann, B. ; Ito, J.* ; Nakagawa, K.* ; Heissmeyer, V. ; Conrad, M. ; Krappmann, D.

MALT1 inhibitor MI-2 induces ferroptosis by direct targeting of GPX4.

Proc. Natl. Acad. Sci. U.S.A. 122:e2507997122 (2025)
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Publication type Article: Journal article
Document type Scientific Article
Language english
Publication Year 2025
HGF-reported in Year 2025
ISSN (print) / ISBN 0027-8424
e-ISSN 1091-6490
Journal Proceedings of the National Academy of Sciences of the United States of America
Quellenangaben Volume: 122, Issue: 20, Pages: , Article Number: e2507997122 Supplement: ,
Publisher National Academy of Sciences
Publishing Place 2101 Constitution Ave Nw, Washington, Dc 20418 Usa
Reviewing status Peer reviewed
Institute(s) Research Unit Signaling and Translation (SAT)
Institute of Metabolism and Cell Death (MCD)
Research Unit Molecular Immune Regulation (AMIR)
POF-Topic(s) 30203 - Molecular Targets and Therapies
Research field(s) Enabling and Novel Technologies
Genetics and Epidemiology
Immune Response and Infection
PSP Element(s) G-509800-002
G-506900-001
G-501712-001
Grants Wilhelm-Sander Foundation
German Research foundation
European Research Council under the European Union
Deutsche Krebshilfe
DOI 10.1073/pnas.2507997122
WOS ID 001496645000001
PubMed ID 40343971
Erfassungsdatum 2025-05-11
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