Teles, P.* ; Costa, R.* ; Bettio, T.* ; Pinheiro, T.* ; Loupa, T.* ; Santos, J.* ; Gil, O.M.* ; Ferrari, P.* ; Zankl, M.
Local DRL estimation and effective dose calculation in paediatric interventional cardiology using measurements and Monte Carlo simulations.
Phys. Med. 135:105023 (2025)
BACKGROUND: Paediatric patients with congenital heart disease benefit greatly from X-ray diagnostic and interventional procedures. However, multiple procedures lead to prolonged exposure to ionizing radiation (IR), raising concerns for secondary long-term health issues. PURPOSE: This study aimed to establish local dose reference levels (LDRLs) for a National Reference Center for Congenital Cardiopathies (NRCCC) in Portugal. Additionally, it estimated effective and organ doses in paediatric patients undergoing coronary angiographies (CAs) using measurements and Monte Carlo simulations. METHODS: LDRLs were determined through statistical analysis of patient registry data from 120 patients recorded between 2022 and 2023. For effective dose estimation, personal dose equivalent values Hp(10) were measured with an anthropomorphic phantom (CIRS ATOM 705) and Raysafe dosimeters, used to validate Monte Carlo (MC) simulations, which were then employed with rescaled paediatric voxel phantoms (GsF Baby and Child), to estimate effective doses and dose conversion coefficients (DCCs) for representative patient anatomies across different age and weight groups. RESULTS: LDRLs for coronary angiographies at the NRCCC showed significant dose variability, indicating dose optimization opportunities. Monte Carlo simulations allowed for organ dose and effective dose calculations. Dose Conversion Coefficients were 1.107, 0.882, 0.719, and 0.524 mSv/Gy·cm2 for newborn, 1 year-old, 5 year-old and 10 year-old groups respectively. A strong linear correlation between effective dose and air-kerma area product (KAP) was observed. CONCLUSIONS: The study highlights the strong correlation between effective dose and KAP, offering a practical framework for estimating patient doses and enhancing radiation safety protocols in clinical practice.
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Publication type
Article: Journal article
Document type
Scientific Article
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Keywords
Dose Conversion Coefficients (dccs) ; Dose Reference Levels (drls) ; Effective Dose Estimation ; Monte Carlo Simulations ; Organ Dose Assessment ; Paediatric Interventional Cardiology ; Voxel Phantoms; Diagnostic Reference Levels; Organ; Catheterizations
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Language
english
Publication Year
2025
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0
HGF-reported in Year
2025
ISSN (print) / ISBN
1120-1797
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1724-191X
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Volume: 135,
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Article Number: 105023
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Elsevier
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125 London Wall, London, England
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Peer reviewed
POF-Topic(s)
30203 - Molecular Targets and Therapies
Research field(s)
Radiation Sciences
PSP Element(s)
G-501391-001
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Erfassungsdatum
2025-06-30