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Prokisch, H. ; Andreoli, C.* ; Ahting, U.* ; Heiss, K.* ; Ruepp, A. ; Scharfe, C.* ; Meitinger, T.

MitoP2: The mitochondrial proteome database-now including mouse data.

Nucleic Acids Res. 34, D705-D711 (2006)
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The MitoP2 database (http://www.mitop.de) integrates information on mitochondrial proteins, their molecular functions and associated diseases. The central database features are manually annotated reference proteins localized or functionally associated with mitochondria supplied for yeast, human and mouse. MitoP2 enables (i) the identification of putative orthologous proteins between these species to study evolutionarily conserved functions and pathways; (ii) the integration of data from systematic genome-wide studies such as proteomics and deletion phenotype screening; (iii) the prediction of novel mitochondrial proteins using data integration and the assignment of evidence scores; and (iv) systematic searches that aim to find the genes that underlie common and rare mitochondrial diseases. The data and analysis files are referenced to data sources in PubMed and other online databases and can be easily downloaded. MitoP2 users can explore the relationship between mitochondrial dysfunctions and disease and utilize this information to conduct systems biology approaches on mitochondria.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter C-OXIDASE DEFICIENCY; SACCHAROMYCES-CEREVISIAE; GLOBAL ANALYSIS; YEAST; PROTEINS; GENOME; EXPRESSION; SCALE; IDENTIFICATION; KNOWLEDGEBASE
Sprache englisch
Veröffentlichungsjahr 2006
HGF-Berichtsjahr 0
ISSN (print) / ISBN 0305-1048
e-ISSN 1362-4962
Zeitschrift Nucleic Acids Research
Quellenangaben Band: 34, Heft: SI, Seiten: D705-D711 Artikelnummer: , Supplement: ,
Verlag Oxford University Press
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Human Genetics (IHG)
Institute of Bioinformatics and Systems Biology (IBIS)
POF Topic(s) 30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
30505 - New Technologies for Biomedical Discoveries
Forschungsfeld(er) Genetics and Epidemiology
Enabling and Novel Technologies
PSP-Element(e) G-500700-001
G-503700-001
PubMed ID 16381964
DOI 10.1093/nar/gkj127
WOS ID 000239307700149
Erfassungsdatum 2006-04-04
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