PuSH - Publikationsserver des Helmholtz Zentrums München: Impact of magnetic field strength on resolution and sensitivity of proton resonances in biological solids.

Informationen

Hinweise zu Qualitätskriterien von Zeitschriften

Open-Access-Richtlinie der Helmholtz-Gemeinschaft 2016

CC Licencences

Metriken für Publikationen

Navigation

Startseite

English

EVA: Veröffentlichen

Neuer EVA Antrag

Recherche

Erweiterte Suche

Durchblättern nach ...

... HMGU-Autoren/Konsortien

... Organisationsstruktur

... Zeitschriften

... Publikationstypen

... Forschungsdaten

... Arbeitsgruppen

... Erscheinungsjahr

Publikationen im Überblick

Statistik

HGF Fortschrittsbericht

OA Publikationen

Eintragen

Neue Publikation eintragen

Neue Publikation holen aus...

...EVA

Fehlende Publikation melden

Highlights

Suche

Hilfe & Kontakt

Ansprechpartner

Hilfe

Datenschutz

Helmholtz Open Science

Bibliometrische Indikatoren

SHERPA/RoMEO

DOAJ

Export:

Text

Endnote (RIS) BIB

BibTeX

Xue, K. ; Sarkar, R. ; Lalli, D.* ; Koch, B.* ; Pintacuda, G.* ; Tosner, Z.* ; Reif, B.

Impact of magnetic field strength on resolution and sensitivity of proton resonances in biological solids.

J. Phys. Chem. C. 124, 22631-22637 (2020)

Postprint

Forschungsdaten

DOI

	Open Access Green

Abstract
Metriken
Zusatzinfos

Sensitivity and resolution together determine the quality of NMR spectra in biological solids. Higher magic angle spinning frequencies yield a more efficient suppression of the coupling network and enable atomic-level investigations of protonated protein samples. On the other hand, truncation effects induced by higher magnetic fields have an impact on the achievable sensitivity and resolution. In this work, we address the question of how the proton dipolar coupling network affects the magnetic field strength-dependent gains in sensitivity and resolution. We find that-beyond the canonical B-0(3/2) dependence-an additional factor of 2 in sensitivity can be achieved for residues embedded in the core of the protein, when the static magnetic field induces a transition from the strong- to the weak-coupling limit. The experiments are carried out using a selectively methyl-protonated ((13)CH3) alpha-spectrin SH3 sample, at magnetic field strengths of 11.75 T (H-1 Larmor frequency of 500 MHz) and 23.5 T (H-1 Larmor frequency of 1 GHz).

Impact Factor

Scopus SNIP

Web of Science
Times Cited

Scopus
Cited By

Altmetric

4.189

1.063