PuSH - Publikationsserver des Helmholtz Zentrums München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
de Sá E Silva, D.M.* ; Thaitumu, M.* ; Theodoridis, G.* ; Witting, M. ; Gika, H.*

Volumetric absorptive microsampling in the analysis of endogenous metabolites.

Metabolites 13:24 (2023)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Volumetric absorptive microsampling (VAMS) has arisen as a relevant tool in biological analysis, offering simplified sampling procedures and enhanced stability. Most of the attention VAMS has received in the past decade has been from pharmaceutical research, with most of the published work employing VAMS targeting drugs or other exogenous compounds, such as toxins and pollutants. However, biomarker analysis by employing blood microsampling has high promise. Herein, a comprehensive review on the applicability of VAMS devices for the analysis of endogenous metabolites/biomarkers was performed. The study presents a full overview of the analysis process, incorporating all the steps in sample treatment and validation parameters. Overall, VAMS devices have proven to be reliable tools for the analysis of endogenous analytes with biological importance, often offering improved analyte stability in comparison with blood under ambient conditions as well as a convenient and straightforward sample acquisition model.
Impact Factor
Scopus SNIP
Altmetric
4.100
0.000
Tags
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern

Zusatzinfos bearbeiten
Eigene Tags bearbeiten
Privat
Eigene Anmerkung bearbeiten
Privat
Auf Publikationslisten für
Homepage nicht anzeigen
Als besondere Publikation
markieren
Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Analytical Validation ; Biomarkers ; Blood Microsampling ; Clinical Application ; Endogenous Metabolites ; Volumetric Absorptive Microsampling (vams); Whole-blood; Quantitative Bioanalysis; Lc-ms/ms; Thiamine Status; Hematocrit; Devices; Plasma; Vams; Quantification; Validation
Sprache englisch
Veröffentlichungsjahr 2023
HGF-Berichtsjahr 2023
ISSN (print) / ISBN 2218-1989
e-ISSN 2218-1989
Zeitschrift Metabolites
Quellenangaben Band: 13, Heft: 10, Seiten: , Artikelnummer: 24 Supplement: ,
Verlag MDPI
Verlagsort St Alban-anlage 66, Ch-4052 Basel, Switzerland
Begutachtungsstatus Peer reviewed
Institut(e) CF Metabolomics & Proteomics (CF-MPC)
POF Topic(s) 30505 - New Technologies for Biomedical Discoveries
Forschungsfeld(er) Enabling and Novel Technologies
PSP-Element(e) A-630710-001
Förderungen Marie Curie Actions (MSCA)
European Union Horizon 2020, Marie Curie Actions
DOI 10.3390/metabo13101038
WOS ID 001090027900001
Scopus ID 85175321229
PubMed ID 37887363
Erfassungsdatum 2023-11-28
[➜Korrektur melden]