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MicroRNAs of Epstein-Barr virus control innate and adaptive anti-viral immunity.
J. Virol. 91:e01667-16 (2017)
More than 90% of humanity is infected with Epstein-Barr virus (EBV) lifelong. While infection is usually controlled by the immune system, the human host fails to completely eliminate the pathogen. Several herpesviral proteins are known that act as immunoevasins preventing or reducing recognition of EBV-infected cells. Only recently, microRNAs of EBV were identified to reduce immune recognition further. This Gem summarizes what we know about immunomodulatory miRNAs of herpesviruses.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Cancer ; Human Herpesviruses ; Immune Evasion ; Immune Surveillance ; Microrna; T-cell Responses; Noncoding Rnas; Nasopharyngeal Carcinoma; Encoded Micrornas; Viral Mirnas; Ebv; Expression; Infection; Target; Modulation
ISSN (print) / ISBN
0022-538X
e-ISSN
1098-5514
Journal
Journal of Virology
Quellenangaben
Volume: 91,
Issue: 16,
Article Number: e01667-16
Publisher
American Society for Microbiology (ASM)
Publishing Place
Washington
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Research Unit Gene Vector (AGV)