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MicroRNAs of Epstein-Barr virus control innate and adaptive anti-viral immunity.

J. Virol. 91:e01667-16 (2017)
Publ. Version/Full Text Postprint DOI PMC
Open Access Green
More than 90% of humanity is infected with Epstein-Barr virus (EBV) lifelong. While infection is usually controlled by the immune system, the human host fails to completely eliminate the pathogen. Several herpesviral proteins are known that act as immunoevasins preventing or reducing recognition of EBV-infected cells. Only recently, microRNAs of EBV were identified to reduce immune recognition further. This Gem summarizes what we know about immunomodulatory miRNAs of herpesviruses.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Cancer ; Human Herpesviruses ; Immune Evasion ; Immune Surveillance ; Microrna; T-cell Responses; Noncoding Rnas; Nasopharyngeal Carcinoma; Encoded Micrornas; Viral Mirnas; Ebv; Expression; Infection; Target; Modulation
Language english
Publication Year 2017
HGF-reported in Year 2017
ISSN (print) / ISBN 0022-538X
e-ISSN 1098-5514
Quellenangaben Volume: 91, Issue: 16, Pages: , Article Number: e01667-16 Supplement: ,
Publisher American Society for Microbiology (ASM)
Publishing Place Washington
Reviewing status Peer reviewed
POF-Topic(s) 30203 - Molecular Targets and Therapies
Research field(s) Immune Response and Infection
PSP Element(s) G-501500-001
Scopus ID 85026322795
PubMed ID 28592533
Erfassungsdatum 2017-07-17